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Pathogens, Volume 14, Issue 1

January 2025 - 103 articles

Cover Story: Human cytomegalovirus (HCMV) is a pervasive virus that infects most of the human population, posing serious risks in congenital infections and among immunocompromised individuals. Despite its ubiquity, the factors that dictate the outcomes of HCMV infections remain elusive. Fascinatingly, a wide range of HCMV strains circulates globally worldwide, and the quest to identify pathogenic strains has captivated scientists. Understanding CMV's genetic diversity and evolutionary dynamics is crucial for elucidating its pathogenesis and developing effective therapeutic interventions. This review offers an in-depth exploration of CMV's genetic diversity and evolution, focusing on the role of different genotypes in viral pathogenesis. View this paper

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Articles (103)

  • Article
  • Open Access
1,479 Views
12 Pages

Epidemiological Analysis of Fungal Infection Disease in Pediatric Population: Focus on Hospitalization from 2007 to 2022 in Veneto Region in Italy

  • Lorenzo Chiusaroli,
  • Claudia Cozzolino,
  • Silvia Cocchio,
  • Mario Saia,
  • Carlo Giaquinto,
  • Daniele Donà and
  • Vincenzo Baldo

18 January 2025

Fungal infections (FIs) are widespread globally, affecting both immunocompromised and immunocompetent children, with varying clinical implications based on age and comorbidities. In immunocompromised children, particularly those with hematologic onco...

  • Article
  • Open Access
1,268 Views
13 Pages

Towards Detecting Associations of Canine Astrovirus and Caliciviruses with Health and Living Characteristics of Dogs in Greece

  • Efthymia Stamelou,
  • Konstantinos Papageorgiou,
  • Dimitrios Papadopoulos,
  • Georgios Delis,
  • Dimitrios Chatzopoulos,
  • Zoi Athanasakopoulou,
  • Efstratios Moschidis,
  • Evanthia Petridou and
  • Spyridon K. Kritas

18 January 2025

Astroviruses and caliciviruses are important causative agents of gastroenteritis in humans worldwide. They have been detected in a variety of animal species, including dogs, but their role in the induction of disease in animals remains uncertain. In...

  • Review
  • Open Access
2 Citations
3,398 Views
22 Pages

The Importance of Lung Innate Immunity During Health and Disease

  • Gusty Rizky Teguh Ryanto,
  • Ratoe Suraya and
  • Tatsuya Nagano

17 January 2025

The lung is a vital organ for the body as the main source of oxygen input. Importantly, it is also an internal organ that has direct contact with the outside world. Innate immunity is a vital protective system in various organs, whereas, in the case...

  • Communication
  • Open Access
3 Citations
1,795 Views
12 Pages

Genomic and Drug Resistance Profile of Bovine Multidrug-Resistant Escherichia coli Isolated in Kazakhstan

  • Pavel G. Alexyuk,
  • Andrey P. Bogoyavlenskiy,
  • Yergali S. Moldakhanov,
  • Kuralay S. Akanova,
  • Adolat N. Manakbayeva,
  • Timur Kerimov,
  • Vladimir E. Berezin and
  • Madina S. Alexyuk

17 January 2025

While studying the prevalence and profile of antibiotic resistance among E. coli isolated from the feces of calves with signs of colibacillosis, a strain with a wide spectrum of drug resistance was isolated. Whole-genome sequencing, followed by bioin...

  • Article
  • Open Access
4 Citations
2,341 Views
15 Pages

Maternal Infections, Antibiotics, Steroid Use, and Diabetes Mellitus Increase Risk of Early-Onset Sepsis in Preterm Neonates: A Nationwide Population-Based Study

  • Hao-Yuan Lee,
  • Yu-Lung Hsu,
  • Wen-Yuan Lee,
  • Kuang-Hua Huang,
  • Ming-Luen Tsai,
  • Chyi-Liang Chen,
  • Yu-Chia Chang and
  • Hung-Chih Lin

17 January 2025

The global evolution of pathogens causing early-onset sepsis (EOS), a critical condition in preterm infants, necessitates a re-evaluation of risk factors to develop updated prevention and treatment strategies. This nationwide case–control study...

  • Communication
  • Open Access
1 Citations
1,703 Views
9 Pages

Pradofloxacin Minimum Inhibitory Concentration Profiling of Streptococcus suis Isolates: Insights into Antimicrobial Susceptibility in Swine

  • Jessica Risser,
  • Ronald Tessman,
  • Don Bade,
  • Orhan Sahin,
  • Maria J. Clavijo,
  • Saumya Dhup and
  • Patrick Hoffmann

17 January 2025

This study evaluated the minimum inhibitory concentration (MIC) of pradofloxacin against various swine respiratory pathogens, including Bordetella bronchiseptica, Glaesserella parasuis, Mycoplasma hyopneumoniae, Pasteurella multocida, and Streptococc...

  • Article
  • Open Access
2 Citations
2,004 Views
19 Pages

Inverted Patterns of Schistosomiasis and Fascioliasis and Risk Factors Among Humans and Livestock in Northern Tanzania

  • Ephrasia A. Hugho,
  • Yakob P. Nagagi,
  • Lucille J. Lyaruu,
  • Victor V. Mosha,
  • Ndealilia Senyael,
  • Magweiga M. Mwita,
  • Ruth W. Mabahi,
  • Violet M. Temba,
  • Mapulish Hebel and
  • Mohamed Nyati
  • + 3 authors

17 January 2025

Fascioliasis and schistosomiasis are parasitic trematodiases of public health and economic concern in humans and livestock. However, data on the distribution and risk factors for fascioliasis remain limited, while epidemiological gaps hinder schistos...

  • Review
  • Open Access
2 Citations
4,369 Views
21 Pages

Parasites in Sewage: Legal Requirements and Diagnostic Tools

  • Oliwia Obuch-Woszczatyńska,
  • Klaudia Bylińska,
  • Małgorzata Krzyżowska,
  • Karol Korzekwa and
  • Piotr Bąska

16 January 2025

Despite the vast amount of water on Earth, only a small percent is suitable for consumption, and these resources are diminishing. Moreover, water resources are unevenly distributed, leading to significant disparities in access to drinking water betwe...

  • Article
  • Open Access
1 Citations
1,563 Views
10 Pages

Prevalence of Leptospira spp. in Lithuanian Wild Boars (Sus scrofa)

  • Birutė Karvelienė,
  • Inga Stadalienė,
  • Jūratė Rudejevienė,
  • Evelina Burbaitė,
  • Dalia Juodžentė,
  • Marius Masiulis,
  • Jūratė Buitkuvienė,
  • Jurgita Šakalienė and
  • Gintaras Zamokas

16 January 2025

Leptospira is a bacteria responsible for a widespread zoonosis that affects both humans and animals. Leptospirosis is a challenging pathology to diagnose and treat since its signs are unspecific and symptoms vary greatly. The disease seems to be high...

  • Article
  • Open Access
1 Citations
1,190 Views
17 Pages

16 January 2025

The papillomavirus E2 protein regulates the transcription, replication, and segregation of viral episomes within the host cell. A multitude of post-translational modifications have been identified which control E2 functions. A highly conserved di-lys...

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Pathogens - ISSN 2076-0817