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Pathogens, Volume 12, Issue 6

June 2023 - 107 articles

Cover Story: Neuromeningeal cryptococcosis is a life-threatening infection of the central nervous system, caused by encapsulated yeast belonging to the Cryptococcus neoformans and Cryptococcus gattii species complexes. There is an increase in resistance to fluconazole for yeasts of the C. gattii species complex, and the virulence is variable according to the genotype. We demonstrated that fluconazole-induced resistant strains are less virulent when compared to the original susceptible strains. In contrast, the clinically resistant strain maintains its virulence compared to fluconazole-susceptible strains of the same sequence type. View this paper
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Articles (107)

  • Review
  • Open Access
33 Citations
4,711 Views
14 Pages

The extensive use of antibiotics in animal production has led to the development of antibiotic-resistant microorganisms and the search for alternative antimicrobial agents in animal production. One such compound may be antimicrobial peptides (AMPs),...

  • Article
  • Open Access
5 Citations
4,415 Views
17 Pages

Plectranthus amboinicus (Indian borage) has been extensively studied for its medicinal properties, which can be exploited to develop new antimicrobial therapeutics. The current study investigated the effect of Plectranthus amboinicus leaf extracts on...

  • Article
  • Open Access
4 Citations
4,556 Views
19 Pages

TRIM16 Overexpression in HEK293T Cells Results in Cell Line-Specific Antiviral Activity

  • Lance R. Nigos,
  • Nichollas E. Scott,
  • Andrew G. Brooks,
  • Malika Ait-Goughoulte,
  • Sarah L. Londrigan,
  • Patrick. C. Reading and
  • Rubaiyea Farrukee

Host cell restriction factors are intracellular proteins that can inhibit virus replication. Characterisation of novel host cell restriction factors can provide potential targets for host-directed therapies. In this study, we aimed to assess a member...

  • Review
  • Open Access
11 Citations
9,553 Views
21 Pages

Human angiostrongylosis is an emerging zoonosis caused by the larvae of three species of metastrongyloid nematodes of the genus Angiostrongylus, with Angiostrongylus cantonensis (Chen, 1935) being dominant across the world. Its obligatory heteroxenou...

  • Article
  • Open Access
3 Citations
2,740 Views
21 Pages

Risk Factors for Hepatitis E Virus Infection and Eating Habits in Kidney Transplant Recipients

  • Eva Wu,
  • Nadine Koch,
  • Friederike Bachmann,
  • Marten Schulz,
  • Evelyn Seelow,
  • Ulrike Weber,
  • Johannes Waiser,
  • Fabian Halleck,
  • Mirko Faber and
  • Claus-Thomas Bock
  • + 5 authors

There is a significant risk for ongoing and treatment-resistant courses of hepatitis E virus (HEV) infection in patients after solid organ transplantation. The aim of this study was to identify risk factors for the development of hepatitis E, includi...

  • Article
  • Open Access
4 Citations
2,043 Views
13 Pages

Estimating the Impact of Consecutive Blood Meals on Vector Competence of Aedes albopictus for Chikungunya Virus

  • Eva Veronesi,
  • Anca Paslaru,
  • Julia Ettlin,
  • Damiana Ravasi,
  • Eleonora Flacio,
  • Matteo Tanadini and
  • Valeria Guidi

The continuous expansion of Aedes albopictus in Europe and the increases in autochthonous arboviruses transmissions in the region urge a better understanding of the virus transmission dynamic. Recent work described enhanced chikungunya virus (CHIKV)...

  • Article
  • Open Access
9 Citations
3,177 Views
12 Pages

Dose-Dependent Inhibitory Effect of Probiotic Lactobacillus plantarum on Streptococcus mutans-Candida albicans Cross-Kingdom Microorganisms

  • Jianhang Bao,
  • Xinyan Huang,
  • Yan Zeng,
  • Tong Tong Wu,
  • Xingyi Lu,
  • Gina Meng,
  • Yanfang Ren and
  • Jin Xiao

Dental caries is one of the most common chronic diseases worldwide. Streptococcus mutans and Candida albicans are two major pathogens associated with dental caries. Several recent studies revealed that Lactobacillus plantarum inhibits S. mutans and C...

  • Article
  • Open Access
1,590 Views
16 Pages

Barriers with Valve Mechanisms Are Predicted to Protect Crops from Slug Carriers of Rat Lungworm Disease

  • Genevieve C. Pang,
  • Amy T. Hou,
  • Ryan Tamashiro,
  • Kristin M. Mills and
  • Lorrin W. Pang

Angiostrongyliasis (Rat Lungworm disease) is an emerging parasitic disease caused by the ingestion of gastropods infected with the neurotropic nematode Angiostrongylus cantonensis. The reduction of crop infestation with infected slug carriers may var...

  • Article
  • Open Access
4 Citations
2,745 Views
25 Pages

The Immune Response in the Uteri and Placentae of Chlamydia abortus-Infected Ewes and Its Association with Pregnancy Outcomes

  • Sergio Gaston Caspe,
  • David Andrew Ewing,
  • Morag Livingstone,
  • Clare Underwood,
  • Elspeth Milne,
  • Neil Donald Sargison,
  • Sean Ranjan Wattegedera and
  • David Longbottom

The enzootic abortion of ewes, caused by the bacterium Chlamydia abortus (C. abortus), is one of the main causes of abortion in sheep. There are multiple contributory factors, including chlamydial growth, host immune response, and hormonal balance, t...

  • Article
  • Open Access
6 Citations
2,544 Views
15 Pages

Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus by Disrupting Virus Entry

  • Caisheng Zhang,
  • Huan Chen,
  • Liumei Sun,
  • Pu Zhao,
  • Chuanxiang Qi,
  • Ying Yang,
  • Anqi Si,
  • Yingjuan Qian and
  • Yong-Sam Jung

The porcine epidemic diarrhea virus (PEDV), belonging to the α-coronavirus, is the causative agent of porcine epidemic diarrhea (PED). Presently, protection from the existing PEDV vaccine is not effective. Therefore, anti-PEDV compounds should...

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Pathogens - ISSN 2076-0817Creative Common CC BY license