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Journal of Personalized Medicine, Volume 14, Issue 6

June 2024 - 118 articles

Cover Story: The shift towards personalized cancer medicine (PCM) represents a significant transformation in cancer care, emphasizing tailored treatments based on the genetic understanding of cancer at the cellular level. This review draws on the recent literature to explore key factors influencing PCM implementation, highlighting the role of innovative leadership, interdisciplinary collaboration, and coordinated funding and regulatory strategies. Success in PCM relies on overcoming challenges such as integrating diverse medical disciplines, securing sustainable investment for shared infrastructures, and navigating complex regulatory landscapes. Effective leadership fosters a culture of innovation and teamwork, which is essential for translating complex biological insights into personalized treatment strategies. View this paper
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Articles (118)

  • Article
  • Open Access
1,649 Views
11 Pages

20 June 2024

The rotational alignment of the femoral component in total knee arthroplasty (TKA) is considered an important factor, but it is still difficult to assess intraoperatively. This study was conducted to identify anatomical parameters for femoral rotatio...

  • Review
  • Open Access
3 Citations
5,023 Views
15 Pages

20 June 2024

Fibromyalgia and osteoarthritis are among the most prevalent rheumatic conditions worldwide. Nonpharmacological interventions have gained scientific endorsements as the preferred initial treatments before resorting to pharmacological modalities. Repe...

  • Article
  • Open Access
1 Citations
2,440 Views
10 Pages

Calcium-Free Dialysate Hemodialysis: A Simplified Approach

  • Alexandra Corbu,
  • Florian Terrec,
  • Paolo Malvezzi,
  • Arnaud Jouzier,
  • Thomas Jouve,
  • Lionel Rostaing and
  • Hamza Naciri Bennani

20 June 2024

Intermittent hemodialysis (HD) in high-bleeding-risk patients presents a challenge as circuit anticoagulation using heparin is contraindicated in such cases. Recently, the use of calcium-free citrate-containing dialysate with calcium supplementation...

  • Article
  • Open Access
2 Citations
3,530 Views
10 Pages

Chronic Pelvic Pain in Congestion Pelvic Syndrome: Clinical Impact and Electromyography Pelvic Floor Activity Prior to and after Endovascular Treatment

  • Fabio Corvino,
  • Francesco Giurazza,
  • Milena Coppola,
  • Antonio Tomasello,
  • Francesco Coletta,
  • Crescenzo Sala,
  • Romolo Villani,
  • Bernardo Maria de Martino,
  • Antonio Corvino and
  • Raffaella Niola

20 June 2024

Background: This study aims to characterize the clinical impact of endovascular treatment in Chronic Pelvic Pain (CPP) patients due to Pelvic Congestion Syndrome (PCS) and to assess the diagnostic value of surface electromyography (sEMG) studies of p...

  • Article
  • Open Access
1 Citations
3,215 Views
11 Pages

20 June 2024

Posterior spinal fusion for adolescent idiopathic scoliosis (AIS) causes severe postoperative pain. Thoracic paravertebral block (PVB) provides excellent analgesia during various surgeries. We examined the effects of PVB on postoperative analgesia in...

  • Article
  • Open Access
2 Citations
1,483 Views
12 Pages

Prediction of Cesarean Section for Intrapartum Fetal Compromise: A Multivariable Model from a Prospective Observational Approach

  • Blanca Novillo-Del Álamo,
  • Alicia Martínez-Varea,
  • Mar Nieto-Tous,
  • Carmen Padilla-Prieto,
  • Fernando Modrego-Pardo,
  • Silvia Bello-Martínez de Velasco,
  • María Victoria García-Florenciano and
  • José Morales-Roselló

20 June 2024

Objective: A cesarean section for intrapartum fetal compromise (IFC) is performed to avoid potential damage to the newborn. It is, therefore, crucial to develop an accurate prediction model that can anticipate, prior to labor, which fetus may be at r...

  • Article
  • Open Access
1 Citations
1,619 Views
11 Pages

Clinical Characteristics and Prognosis of Older Patients with Coronavirus Disease 2019 Requiring Mechanical Ventilation

  • Green Hong,
  • Da Hyun Kang,
  • Sunghoon Park,
  • Su Hwan Lee,
  • Onyu Park,
  • Taehwa Kim,
  • Hye Ju Yeo,
  • Jin Ho Jang,
  • Woo Hyun Cho and
  • Song I Lee

19 June 2024

An older age is associated with severe progression and poor prognosis in coronavirus disease 2019 (COVID-19), and mechanical ventilation is often required. The specific characteristics of older patients undergoing mechanical ventilation and their pro...

  • Review
  • Open Access
11 Citations
5,390 Views
15 Pages

Future Horizons: The Potential Role of Artificial Intelligence in Cardiology

  • Octavian Stefan Patrascanu,
  • Dana Tutunaru,
  • Carmina Liana Musat,
  • Oana Maria Dragostin,
  • Ana Fulga,
  • Luiza Nechita,
  • Alexandru Bogdan Ciubara,
  • Alin Ionut Piraianu,
  • Elena Stamate and
  • Diana Gina Poalelungi
  • + 4 authors

19 June 2024

Cardiovascular diseases (CVDs) are the leading cause of premature death and disability globally, leading to significant increases in healthcare costs and economic strains. Artificial intelligence (AI) is emerging as a crucial technology in this conte...

  • Review
  • Open Access
22 Citations
5,682 Views
20 Pages

19 June 2024

Background/Objectives: Temporomandibular disorder (TMD) is the term used to describe a pathology (dysfunction and pain) in the masticatory muscles and temporomandibular joint (TMJ). There is an apparent upward trend in the publication of dental resea...

  • Systematic Review
  • Open Access
4 Citations
4,236 Views
28 Pages

The Long Journey towards Personalized Targeted Therapy in Poorly Differentiated Thyroid Carcinoma (PDTC): A Case Report and Systematic Review

  • Odysseas Violetis,
  • Panagiota Konstantakou,
  • Ariadni Spyroglou,
  • Antonios Xydakis,
  • Panagiotis B. Kekis,
  • Sofia Tseleni,
  • Denise Kolomodi,
  • Manousos Konstadoulakis,
  • George Mastorakos and
  • Maria Theochari
  • + 2 authors

18 June 2024

Background: Poorly differentiated thyroid carcinoma (PDTC) has an intermediate prognosis between indolent well-differentiated thyroid carcinoma (TC) and anaplastic carcinoma. Herein, we present a case report with a PDTC component, along with a system...

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J. Pers. Med. - ISSN 2075-4426