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Diagnostics, Volume 7, Issue 3

September 2017 - 16 articles

Cover Story: We identified a common anatomical variation in the brachial plexus of a cadaveric sample in which nerve fibers course through the anterior scalene muscle, potentially becoming impinged, which could lead to a predisposition for neurogenic thoracic outlet syndrome (nTOS). Using ultrasonography, we identified this variant in living subjects and found that individuals with nTOS symptoms were significantly more likely to have this variation. The implications for the diagnosis and treatment of nTOS are discussed in detail. View this paper
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Articles (16)

  • Review
  • Open Access
61 Citations
13,035 Views
12 Pages

Recent Progress in the Development of Diagnostic Tests for Malaria

  • Francis D. Krampa,
  • Yaw Aniweh,
  • Gordon A. Awandare and
  • Prosper Kanyong

The impact of malaria on global health has continually prompted the need to develop effective diagnostic strategies. In malaria endemic regions, routine diagnosis is hampered by technical and infrastructural challenges to laboratories. These laborato...

  • Review
  • Open Access
31 Citations
10,055 Views
8 Pages

The Usefulness of Contrast-Enhanced Ultrasound in the Assessment of Early Kidney Transplant Function and Complications

  • Sara Álvarez Rodríguez,
  • Vital Hevia Palacios,
  • Enrique Sanz Mayayo,
  • Victoria Gómez Dos Santos,
  • Víctor Díez Nicolás,
  • María Dolores Sánchez Gallego,
  • Javier Lorca Álvaro and
  • Francisco Javier Burgos Revilla

Objectives: The routine diagnostic method for assessment of renal graft dysfunction is Doppler ultrasound. However, contrast-enhanced ultrasound (CEUS) may provide more information about parenchymal flow and vascular status of kidney allografts. The...

  • Review
  • Open Access
53 Citations
13,239 Views
9 Pages

Development of Multiplexed Infectious Disease Lateral Flow Assays: Challenges and Opportunities

  • Khayriyyah Mohd Hanafiah,
  • Norsyahida Arifin,
  • Yazmin Bustami,
  • Rahmah Noordin,
  • Mary Garcia and
  • David Anderson

Lateral flow assays (LFAs) are the mainstay of rapid point-of-care diagnostics, with the potential to enable early case management and transform the epidemiology of infectious disease. However, most LFAs only detect single biomarkers. Recognizing the...

  • Brief Report
  • Open Access
14 Citations
9,081 Views
7 Pages

Using Naïve Bayesian Analysis to Determine Imaging Characteristics of KRAS Mutations in Metastatic Colon Cancer

  • Yash Pershad,
  • Siddharth Govindan,
  • Amy K. Hara,
  • Mitesh J. Borad,
  • Tanios Bekaii-Saab,
  • Alex Wallace,
  • Hassan Albadawi and
  • Rahmi Oklu

Genotype, particularly Ras status, greatly affects prognosis and treatment of liver metastasis in colon cancer patients. This pilot aimed to apply word frequency analysis and a naive Bayes classifier on radiology reports to extract distinguishing ima...

  • Interesting Images
  • Open Access
4 Citations
7,367 Views
3 Pages

18F-FDG PET/CT Findings in a Patient with Chikungunya Virus Infection

  • Michala Vaaben Rose,
  • Anna Sophie L. Kjaer,
  • Elena Markova and
  • Jesper Graff

We present a case demonstrating the diagnostic work-up and follow-up of a patient with Chikungunya infection. An 18F-FDG PET/CT performed four weeks after debut of symptoms revealed pathological 18F-FDG uptake in enlarged lymph nodes on both side of...

  • Article
  • Open Access
28 Citations
9,556 Views
15 Pages

Incorporating Oxygen-Enhanced MRI into Multi-Parametric Assessment of Human Prostate Cancer

  • Heling Zhou,
  • Rami R. Hallac,
  • Qing Yuan,
  • Yao Ding,
  • Zhongwei Zhang,
  • Xian-Jin Xie,
  • Franto Francis,
  • Claus G. Roehrborn,
  • R. Douglas Sims and
  • Daniel N. Costa
  • + 2 authors

Hypoxia is associated with prostate tumor aggressiveness, local recurrence, and biochemical failure. Magnetic resonance imaging (MRI) offers insight into tumor pathophysiology and recent reports have related transverse relaxation rate (R2*) and longi...

  • Article
  • Open Access
3 Citations
6,812 Views
13 Pages

Feasibility Study of an Optical Caustic Plasmonic Light Scattering Sensor for Human Serum Anti-Dengue Protein E Antibody Detection

  • Antonio A. García,
  • Lina S. Franco,
  • Miguel A. Pirez-Gomez,
  • José L. Pech-Pacheco,
  • Jorge F. Mendez-Galvan,
  • Carlos Machain-Williams,
  • Lourdes Talavera-Aguilar,
  • José H. Espinosa-Carrillo,
  • Miriam M. Duarte-Villaseñor and
  • Christian Be-Ortiz
  • + 3 authors

Antibody detection and accurate diagnosis of tropical diseases is essential to help prevent the spread of disease. However, most detection methods lack cost-effectiveness and field portability, which are essential features for achieving diagnosis in...

  • Review
  • Open Access
50 Citations
46,096 Views
12 Pages

The diagnosis of brachial plexus compression—either neurogenic thoracic outlet syndrome (NTOS) or neurogenic pectoralis minor syndrome (NPMS)—is based on old fashioned history and physical examination. Tests, such as scalene muscle and pectoralis min...

  • Review
  • Open Access
79 Citations
18,948 Views
18 Pages

Since the discovery of the two-dimensional (2D) carbon material, graphene, just over a decade ago, the development of graphene-based field effect transistors (G-FETs) has become a widely researched area, particularly for use in point-of-care biomedic...

  • Review
  • Open Access
22 Citations
9,927 Views
9 Pages

New Biomarkers and Diagnostic Tools for the Management of Fever in Low- and Middle-Income Countries: An Overview of the Challenges

  • Camille Escadafal,
  • Christian Nsanzabana,
  • Julie Archer,
  • Violet Chihota,
  • William Rodriguez and
  • Sabine Dittrich

A lack of simple, inexpensive, and rapid diagnostic tests for febrile illnesses other than malaria leads to overtreatment with antibiotics for those who test negative for malaria, and contributes to the global rise in antimicrobial resistance. New te...

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Diagnostics - ISSN 2075-4418