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Diagnostics, Volume 6, Issue 4

2016 December - 10 articles

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Articles (10)

  • Review
  • Open Access
61 Citations
9,514 Views
15 Pages

Oral Biofluid Biomarker Research: Current Status and Emerging Frontiers

  • Austin Wang,
  • Chris P. Wang,
  • Michael Tu and
  • David T.W. Wong

Salivary diagnostics is a rapidly advancing field that offers clinicians and patients the potential of rapid, noninvasive diagnostics with excellent accuracy. In order for the complete realization of the potential of saliva, however, extensive profil...

(This article belongs to the Special Issue Oral Fluid-Based Molecular Diagnostics)
  • Review
  • Open Access
14 Citations
8,110 Views
10 Pages

Advanced hepatocellular carcinoma (HCC) with vascular invasion and/or extrahepatic spread and preserved liver function, according to stage C of the Barcelona Clinic Liver Cancer (BCLC) classification, has a dismal prognosis. The multi-targeted tyrosi...

(This article belongs to the Collection Feature Papers)
  • Review
  • Open Access
132 Citations
23,137 Views
20 Pages

Gold Nanoparticles for Diagnostics: Advances towards Points of Care

  • Mílton Cordeiro,
  • Fábio Ferreira Carlos,
  • Pedro Pedrosa,
  • António Lopez and
  • Pedro Viana Baptista

The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems s...

(This article belongs to the Special Issue Novel Point-of-Care Technologies in Diagnostics)
  • Review
  • Open Access
31 Citations
10,252 Views
16 Pages

Targeted Molecular Imaging in Adrenal Disease—An Emerging Role for Metomidate PET-CT

  • Iosif A. Mendichovszky,
  • Andrew S. Powlson,
  • Roido Manavaki,
  • Franklin I. Aigbirhio and ,
  • Heok Cheow,
  • John R. Buscombe,
  • Mark Gurnell and
  • Fiona J. Gilbert
  • + 3 authors+ 0 author

Adrenal lesions present a significant diagnostic burden for both radiologists and endocrinologists, especially with the increasing number of adrenal ‘incidentalomas’ detected on modern computed tomography (CT) or magnetic resonance imaging (MRI). A k...

(This article belongs to the Special Issue Positron Emission Tomography (PET) in Cardiology and Oncology)
  • Article
  • Open Access
4 Citations
6,900 Views
9 Pages

Detection of pubertal growth peak is vital in orthodontic treatment timing and planning. Gingival crevicular fluid (GCF) contains abundant proteins from different sources and has been proven to be an ideal source of biomarkers. Matrix-assisted laser...

(This article belongs to the Special Issue Oral Fluid-Based Molecular Diagnostics)
  • Article
  • Open Access
26 Citations
8,343 Views
12 Pages

Endogenous Intoxication and Saliva Lipid Peroxidation in Patients with Lung Cancer

  • Lyudmila V. Bel’skaya,
  • Victor K. Kosenok and
  • Gilbert Massard

This research was aimed at a search for regularities in changes to parameters of endogenous intoxication and saliva lipid peroxidation in patients with lung cancer, non-malignant lung diseases, and apparently healthy people. All patients went through...

(This article belongs to the Special Issue Oral Fluid-Based Molecular Diagnostics)
  • Article
  • Open Access
39 Citations
11,337 Views
6 Pages

The Effect of Exercise on Salivary Viscosity

  • Antoon J. M. Ligtenberg,
  • Erwin H. S. Liem,
  • Henk S. Brand and
  • Enno C. I. Veerman

A common experience after exercise is the presence of a thick and sticky saliva layer on the oral surfaces, which causes a feeling of a dry mouth. Since the salivary mucin MUC5B is responsible for the visco-elastic behavior of saliva, in the present...

(This article belongs to the Special Issue Oral Fluid-Based Molecular Diagnostics)
  • Article
  • Open Access
34 Citations
9,942 Views
15 Pages

Exploring the Limits of Cell Adhesion under Shear Stress within Physiological Conditions and beyond on a Chip

  • Melanie E. M. Stamp,
  • Anna M. Jötten,
  • Patrick W. Kudella,
  • Dominik Breyer and ,
  • Florian G. Strobl,
  • Thomas M. Geislinger,
  • Achim Wixforth and
  • Christoph Westerhausen
  • + 3 authors+ 0 author

Cell adhesion processes are of ubiquitous importance for biomedical applications such as optimization of implant materials. Here, not only physiological conditions such as temperature or pH, but also topographical structures play crucial roles, as in...

(This article belongs to the Section Point-of-Care Diagnostics and Devices)
  • Review
  • Open Access
81 Citations
12,683 Views
22 Pages

Fluid Biomarkers of Traumatic Brain Injury and Intended Context of Use

  • Tanya Bogoslovsky,
  • Jessica Gill,
  • Andreas Jeromin,
  • Cora Davis and
  • Ramon Diaz-Arrastia

Traumatic brain injury (TBI) is one of the leading causes of death and disability around the world. The lack of validated biomarkers for TBI is a major impediment to developing effective therapies and improving clinical practice, as well as stimulati...

  • Review
  • Open Access
16 Citations
8,191 Views
10 Pages

The Role of PET/CT Molecular Imaging in the Diagnosis of Recurrence and Surveillance of Patients Treated for Non-Small Cell Lung Cancer

  • Julio Francisco Jiménez-Bonilla,
  • Remedios Quirce,
  • I. Martínez-Rodríguez,
  • María De Arcocha-Torres and ,
  • José Manuel Carril and
  • Ignacio Banzo
  • + 1 author+ 0 author

Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide and its prognosis remains poor. Molecular imaging with 18F-FDG PET/CT can metabolically characterize the nature of lesions as benign or malignant, allowing a better...

(This article belongs to the Special Issue Positron Emission Tomography (PET) in Cardiology and Oncology)
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Diagnostics - ISSN 2075-4418