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Diagnostics, Volume 6, Issue 4

December 2016 - 10 articles

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Articles (10)

  • Review
  • Open Access
55 Citations
8,970 Views
15 Pages

Oral Biofluid Biomarker Research: Current Status and Emerging Frontiers

  • Austin Wang,
  • Chris P. Wang,
  • Michael Tu and
  • David T.W. Wong

Salivary diagnostics is a rapidly advancing field that offers clinicians and patients the potential of rapid, noninvasive diagnostics with excellent accuracy. In order for the complete realization of the potential of saliva, however, extensive profil...

  • Review
  • Open Access
13 Citations
7,613 Views
10 Pages

Advanced hepatocellular carcinoma (HCC) with vascular invasion and/or extrahepatic spread and preserved liver function, according to stage C of the Barcelona Clinic Liver Cancer (BCLC) classification, has a dismal prognosis. The multi-targeted tyrosi...

  • Review
  • Open Access
121 Citations
21,173 Views
20 Pages

Gold Nanoparticles for Diagnostics: Advances towards Points of Care

  • Mílton Cordeiro,
  • Fábio Ferreira Carlos,
  • Pedro Pedrosa,
  • António Lopez and
  • Pedro Viana Baptista

The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems s...

  • Review
  • Open Access
28 Citations
9,475 Views
16 Pages

Targeted Molecular Imaging in Adrenal Disease—An Emerging Role for Metomidate PET-CT

  • Iosif A. Mendichovszky,
  • Andrew S. Powlson,
  • Roido Manavaki,
  • Franklin I. Aigbirhio,
  • Heok Cheow,
  • John R. Buscombe,
  • Mark Gurnell and
  • Fiona J. Gilbert

Adrenal lesions present a significant diagnostic burden for both radiologists and endocrinologists, especially with the increasing number of adrenal ‘incidentalomas’ detected on modern computed tomography (CT) or magnetic resonance imaging (MRI). A k...

  • Article
  • Open Access
4 Citations
6,608 Views
9 Pages

Detection of pubertal growth peak is vital in orthodontic treatment timing and planning. Gingival crevicular fluid (GCF) contains abundant proteins from different sources and has been proven to be an ideal source of biomarkers. Matrix-assisted laser...

  • Article
  • Open Access
24 Citations
7,939 Views
12 Pages

Endogenous Intoxication and Saliva Lipid Peroxidation in Patients with Lung Cancer

  • Lyudmila V. Bel’skaya,
  • Victor K. Kosenok and
  • Gilbert Massard

This research was aimed at a search for regularities in changes to parameters of endogenous intoxication and saliva lipid peroxidation in patients with lung cancer, non-malignant lung diseases, and apparently healthy people. All patients went through...

  • Article
  • Open Access
31 Citations
9,895 Views
6 Pages

The Effect of Exercise on Salivary Viscosity

  • Antoon J. M. Ligtenberg,
  • Erwin H. S. Liem,
  • Henk S. Brand and
  • Enno C. I. Veerman

A common experience after exercise is the presence of a thick and sticky saliva layer on the oral surfaces, which causes a feeling of a dry mouth. Since the salivary mucin MUC5B is responsible for the visco-elastic behavior of saliva, in the present...

  • Article
  • Open Access
30 Citations
9,400 Views
15 Pages

Exploring the Limits of Cell Adhesion under Shear Stress within Physiological Conditions and beyond on a Chip

  • Melanie E. M. Stamp,
  • Anna M. Jötten,
  • Patrick W. Kudella,
  • Dominik Breyer,
  • Florian G. Strobl,
  • Thomas M. Geislinger,
  • Achim Wixforth and
  • Christoph Westerhausen

Cell adhesion processes are of ubiquitous importance for biomedical applications such as optimization of implant materials. Here, not only physiological conditions such as temperature or pH, but also topographical structures play crucial roles, as in...

  • Review
  • Open Access
74 Citations
11,823 Views
22 Pages

Fluid Biomarkers of Traumatic Brain Injury and Intended Context of Use

  • Tanya Bogoslovsky,
  • Jessica Gill,
  • Andreas Jeromin,
  • Cora Davis and
  • Ramon Diaz-Arrastia

Traumatic brain injury (TBI) is one of the leading causes of death and disability around the world. The lack of validated biomarkers for TBI is a major impediment to developing effective therapies and improving clinical practice, as well as stimulati...

  • Review
  • Open Access
16 Citations
7,701 Views
10 Pages

The Role of PET/CT Molecular Imaging in the Diagnosis of Recurrence and Surveillance of Patients Treated for Non-Small Cell Lung Cancer

  • Julio Francisco Jiménez-Bonilla,
  • Remedios Quirce,
  • I. Martínez-Rodríguez,
  • María De Arcocha-Torres,
  • José Manuel Carril and
  • Ignacio Banzo

Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide and its prognosis remains poor. Molecular imaging with 18F-FDG PET/CT can metabolically characterize the nature of lesions as benign or malignant, allowing a better...

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Diagnostics - ISSN 2075-4418