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Diagnostics, Volume 5, Issue 2

June 2015 - 10 articles

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Articles (10)

  • Article
  • Open Access
26 Citations
14,162 Views
15 Pages

The Institute of Medicine recently proposed a new case definition for chronic fatigue syndrome (CFS), as well as a new name, Systemic Exertion Intolerance Disease (SEID). Contrary to the Fukuda et al.’s CFS case definition, there are few exclusionary...

  • Article
  • Open Access
9 Citations
7,648 Views
18 Pages

Adrenal Vein Sampling for Conn’s Syndrome: Diagnosis and Clinical Outcomes

  • Amy R. Deipolyi,
  • Alexander Bailin,
  • Stephan Wicky,
  • Shehab Alansari and
  • Rahmi Oklu

Adrenal vein sampling (AVS) is the gold standard test to determine unilateral causes of primary aldosteronism (PA). We have retrospectively characterized our experience with AVS including concordance of AVS results and imaging, and describe the appro...

  • Review
  • Open Access
57 Citations
12,953 Views
35 Pages

High molecular group box 1 (HMGB1) is a highly conserved member of the HMG-box-family; abundantly expressed in almost all human cells and released in apoptosis; necrosis or by activated immune cells. Once in the extracellular space, HMGB1 can act as...

  • Article
  • Open Access
7 Citations
6,255 Views
9 Pages

Our purpose in this study was to assess the relationship between contrast signal intensity (CI) and concentration of perflubutane microbubbles in a phantom experiment, and to examine the feasibility of this technique for quantitative analysis of vasc...

  • Article
  • Open Access
13 Citations
8,137 Views
11 Pages

Chronic Liver Disease and the Detection of Hepatocellular Carcinoma by [18F]fluorocholine PET/CT

  • Sandi A. Kwee,
  • Linda L. Wong,
  • Brenda Y. Hernandez,
  • Owen T.M. Chan,
  • Miles M. Sato and
  • Naoky Tsai

Positron emission tomography (PET) using the radiopharmaceutical tracer fluorine-18 fluorocholine (FCh) can elucidate tumors based on differences in choline phospholipid metabolism between tumor and surrounding tissue. The feasibility of detecting he...

  • Article
  • Open Access
5 Citations
7,123 Views
12 Pages

A Novel Point-of-Care Biomarker Recognition Method: Validation by Detecting Marker for Diabetic Nephropathy

  • Sahana Pentyala,
  • John Muller,
  • Thomas Tumillo,
  • Avijit Roy,
  • Pooja Mysore and
  • Srinivas Pentyala

23 April 2015

Biological fluid collection to identify and analyze different disease markers is a routine and normal procedure in health care settings. Body fluids are as varied as urine, blood, mucus, cerebrospinal fluid (CSF), tears, semen, etc. The volumes of th...

  • Review
  • Open Access
89 Citations
12,502 Views
58 Pages

Neuroendocrine Carcinomas of the Gastroenteropancreatic System: A Comprehensive Review

  • Emma Elizabeth Ilett,
  • Seppo W. Langer,
  • Ingrid Holst Olsen,
  • Birgitte Federspiel,
  • Andreas Kjær and
  • Ulrich Knigge

To date, empirical literature has generally been considered lacking in relation to neuroendocrine carcinomas (NECs), the highly malignant subgroup of neuroendocrine neoplasms. NECs are often found in the lungs or the gastroenteropancreatic (GEP) syst...

  • Article
  • Open Access
5,264 Views
6 Pages

Dementia diagnosis is important for many different reasons. Firstly, to separate dementia, or major neurocognitive disorder, from MCI (mild cognitive impairment), mild neurocognitive disorder. Secondly, to define the specific underlying brain disorde...

  • Article
  • Open Access
1 Citations
7,021 Views
17 Pages

Pharmacokinetic Analysis of 64Cu-ATSM Dynamic PET in Human Xenograft Tumors in Mice

  • Fan Li,
  • Jesper Tranekjær Jørgensen,
  • Jacob Madsen and
  • Andreas Kjaer

The aim of this study was to evaluate the feasibility to perform voxel-wise kinetic modeling on datasets obtained from tumor-bearing mice that underwent dynamic PET scans with 64Cu-ATSM and extract useful physiological parameters. Methods: Tumor-bea...