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Diagnostics, Volume 14, Issue 17

September-1 2024 - 159 articles

Cover Story: With the growing prevalence of diabetes mellitus, diabetic retinopathy, a major cause of vision loss globally, is on the rise. Traditional diagnostic methods often fall short in early detection, prompting this review to investigate emerging approaches that could enhance care. Technologies such as teleophthalmology, smartphone-based imaging, artificial intelligence with deep learning, and nanotechnology are advancing screening accuracy and accessibility. While these innovations offer promising improvements in early detection and treatment efficiency, challenges such as high costs, insurance coverage limitations, and potential technological biases must be addressed to ensure their effective deployment and broad adoption in diabetic eye care. View this paper
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Articles (159)

  • Article
  • Open Access
1,477 Views
10 Pages

[131I]6ß-Iodomethyl-19-norcholesterol SPECT/CT for the Lateralization of Mineralocorticoid Overproduction in Primary Aldosteronism

  • Sandor Barna,
  • Livia Sira,
  • Harjit Pal Bhattoa,
  • Laszlo Toth,
  • Zsigmond Czine,
  • Lilla Szoboszlay,
  • Edit B. Nagy,
  • Zita Kepes,
  • Ildiko Garai and
  • Miklos Bodor
  • + 2 authors

9 September 2024

Primary: aldosteronism is a frequent cause of secondary hypertension. With access to specialized care, an increasing number of patients with aldosteronism are being identified. Primary aldosteronism is treatable by adrenal surgery if aldosterone exce...

  • Article
  • Open Access
1 Citations
1,294 Views
20 Pages

Optical Methods for Optimizing Fluorescence Imaging Field of View and Image Quality in Surgical Guidance Procedures

  • Jeongmin Seo,
  • Jina Park,
  • Kicheol Yoon,
  • Sangyun Lee,
  • Minchan Kim,
  • Seung Yeob Ryu and
  • Kwang Gi Kim

9 September 2024

Cancer surgery is aimed at complete tumor resection and accurate lymph node detection. However, numerous blood vessels are distributed within the tumor, and the colors of the tumor, blood vessels, and lymph nodes are similar, making observations with...

  • Review
  • Open Access
1 Citations
2,426 Views
11 Pages

Fentanyl and Sudden Death—A Postmortem Perspective for Diagnosing and Predicting Risk

  • Ines Strenja,
  • Elizabeta Dadić-Hero,
  • Manuela Perković and
  • Ivan Šoša

9 September 2024

Sudden, unexpected deaths are extremely difficult for families, especially when the victim is a child. Most sudden deaths occur due to cardiovascular issues, and a smaller number (approximately one-quarter) are attributed to other causes, such as epi...

  • Review
  • Open Access
7 Citations
3,958 Views
12 Pages

Hyperglycemia and Venous Thromboembolism

  • Neha Panchagnula and
  • William Philip Brasher

9 September 2024

Patients with diabetes mellitus (DM) have chronically increased blood glucose and multiple physiologic alterations that place them at elevated risk for vascular disease. Traditionally, this vascular risk has mainly referred to chronic atherosclerosis...

  • Article
  • Open Access
3 Citations
1,432 Views
16 Pages

Can Selected Parameters of Brain Injury Reflect Neuronal Damage in Smoldering Multiple Sclerosis?

  • Natalia Niedziela,
  • Maria Nowak-Kiczmer,
  • Lina Malciene,
  • Mariusz Stasiołek,
  • Jolanta Zalejska-Fiolka,
  • Zenon P. Czuba,
  • Jacek T. Niedziela,
  • Jarosław Szczygieł,
  • Michał Lubczyński and
  • Monika Adamczyk-Sowa

9 September 2024

Background: Inflammatory demyelination and impaired recovery processes result in permanent neurodegeneration and neurological disability in patients with multiple sclerosis (MS). In terms of smoldering MS, chronic neuroinflammation develops in the ea...

  • Article
  • Open Access
2 Citations
3,503 Views
18 Pages

Artificial Intelligence-Based Screening System for Diabetic Retinopathy in Primary Care

  • Marc Baget-Bernaldiz,
  • Benilde Fontoba-Poveda,
  • Pedro Romero-Aroca,
  • Raul Navarro-Gil,
  • Adriana Hernando-Comerma,
  • Angel Bautista-Perez,
  • Monica Llagostera-Serra,
  • Cristian Morente-Lorenzo,
  • Montse Vizcarro and
  • Alejandra Mira-Puerto

9 September 2024

Background: This study aimed to test an artificial intelligence-based reading system (AIRS) capable of reading retinographies of type 2 diabetic (T2DM) patients and a predictive algorithm (DRPA) that predicts the risk of each patient with T2DM of dev...

  • Article
  • Open Access
5 Citations
2,445 Views
11 Pages

9 September 2024

Direct oral anticoagulants (DOACs) are increasingly used for the treatment of thrombosis. While inhibitors of factor IIa and factor Xa have shown effectiveness, the risk of bleeding remains a significant concern. Recently, direct factor XIa inhibitor...

  • Article
  • Open Access
1 Citations
1,630 Views
14 Pages

9 September 2024

Objectives: This study aimed to comprehensively investigate the functional connectivity of ten sub-regions within the premotor and supplementary motor areas (Right and Left Premotor 6d1, 6d2, 6d3, and Right and Left pre-Supplementary Motor (presma) a...

  • Article
  • Open Access
2 Citations
1,915 Views
14 Pages

Enhancing Cone-Beam CT Image Quality in TIPSS Procedures Using AI Denoising

  • Reza Dehdab,
  • Andreas S. Brendlin,
  • Gerd Grözinger,
  • Haidara Almansour,
  • Jan Michael Brendel,
  • Sebastian Gassenmaier,
  • Patrick Ghibes,
  • Sebastian Werner,
  • Konstantin Nikolaou and
  • Saif Afat

9 September 2024

Purpose: This study evaluates a deep learning-based denoising algorithm to improve the trade-off between radiation dose, image noise, and motion artifacts in TIPSS procedures, aiming for shorter acquisition times and reduced radiation with maintained...

  • Article
  • Open Access
4 Citations
3,296 Views
15 Pages

Kinetics of the Lactate to Albumin Ratio in New Onset Sepsis: Prognostic Implications

  • Irene Karampela,
  • Dimitris Kounatidis,
  • Natalia G. Vallianou,
  • Fotis Panagopoulos,
  • Dimitrios Tsilingiris and
  • Maria Dalamaga

8 September 2024

The lactate to albumin ratio (LAR) has been associated with the severity and outcome of critical illness and sepsis. However, there are no studies on the kinetics of the LAR during the early phase of sepsis. Therefore, we aimed to investigate the LAR...

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Diagnostics - ISSN 2075-4418