Next Article in Journal
Assessment of the Status of Patients with Parkinson’s Disease Using Neural Networks and Mobile Phone Sensors
Previous Article in Journal
Long-Term Risk Assessment for Medical Application of Cold Atmospheric Pressure Plasma
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Diagnostics
Volume 10
Issue 4
10.3390/diagnostics10040213
diagnostics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Inter-Observer Agreement of a New Endoscopic Score for Ulcerative Colitis Activity: Preliminary Experience

by
Mariabeatrice Principi
1,*,
Antonella Contaldo
1,
Francesco Paolo Bianchi
2,
Giuseppe Losurdo
1,3,
Andrea Iannone
1,
Enzo Ierardi
1,
Silvio Tafuri
2,
Alfredo Di Leo
1 and
IBD Endoscopy Team Work
†
1
Section of Gastroenterology, Department of Emergency and Organ Transplantation, University “Aldo Moro” of Bari, 70124 Bari, Italy
2
Department of Biomedical Science and Human Oncology, University of Bari “Aldo Moro”, 70124 Bari, Italy
3
PhD Course in Organs and Tissues Transplantation and Cellular Therapies, Department of Emergency and Organ Transplantation, University “Aldo Moro” of Bari, 70124 Bari, Italy
*
Author to whom correspondence should be addressed.
†
A complete list of the IBD Endoscopy Team Work is provided in Appendix A.
Diagnostics 2020, 10(4), 213; https://doi.org/10.3390/diagnostics10040213
Submission received: 27 March 2020 / Revised: 6 April 2020 / Accepted: 7 April 2020 / Published: 12 April 2020
(This article belongs to the Section Medical Imaging and Theranostics)
Browse Figures
Versions Notes

Abstract

Ulcerative colitis (UC) endoscopic scores translate mucosal damage into values standardizing image analysis. Due to potential limits of current endoscopic activity indexes, we have elaborated on a new score, the “Extended Mayo Endoscopic Score (EMES),” and evaluated its inter-observer agreement in a multicenter endoscopy team, comparing concordance with the Mayo subscore. Sixteen UC consecutive patients underwent follow-up colonoscopy. Recorded videos were anonymously loaded on a web platform. Thirteen expert endoscopists evaluated UC activity using both Mayo and EMES. EMES was described in every colon segment: erythema (0: absent, 1: mild, 2: moderate, 3: severe), vascular pattern (0: normal, 1: reduction, 2: disappearance), erosions and ulcers (0: absent, 1: from 1 to 5, 2: 6 to 10, 3: >10). Weighted Fleiss’ kappa with 95% confidence interval (CI) and p-value defined inter-rater agreement. Global inter-observer agreement of EMES was moderate (kappa = 0.56, 95% CI = 0.46–0.67, p < 0.001). The evaluation of each colonic segment showed moderate agreement for all segments: ascending (kappa = 0.46, 95% CI = 0.32–0.60, p < 0.001), transverse (kappa = 0.48, 95% CI = 0.29–0.67, p < 0.001); descending (kappa = 0.49, 95% CI = 0.35–0.64, p < 0.001), sigmoid (kappa = 0.52, 95% CI = 0.39–0.65, p < 0.001) and rectum (kappa = 0.55, 95% CI = 0.42–0.69, p < 0.001). Mayo subscore agreement was similar to global EMES (kappa = 0.53, 95% CI = 0.39–0.66, p = 0.001). Therefore, our report emphasizes the importance of assessing inter-observer agreement for EMES, but also for other known scoring systems, including the Mayo subscore.
Keywords: ulcerative colitis; disease activity; endoscopic scores; Extended Mayo Endoscopic Score ulcerative colitis; disease activity; endoscopic scores; Extended Mayo Endoscopic Score

Share and Cite

MDPI and ACS Style

Principi, M.; Contaldo, A.; Bianchi, F.P.; Losurdo, G.; Iannone, A.; Ierardi, E.; Tafuri, S.; Di Leo, A.; IBD Endoscopy Team Work. Inter-Observer Agreement of a New Endoscopic Score for Ulcerative Colitis Activity: Preliminary Experience. Diagnostics 2020, 10, 213. https://doi.org/10.3390/diagnostics10040213

AMA Style

Principi M, Contaldo A, Bianchi FP, Losurdo G, Iannone A, Ierardi E, Tafuri S, Di Leo A, IBD Endoscopy Team Work. Inter-Observer Agreement of a New Endoscopic Score for Ulcerative Colitis Activity: Preliminary Experience. Diagnostics. 2020; 10(4):213. https://doi.org/10.3390/diagnostics10040213

Chicago/Turabian Style

Principi, Mariabeatrice, Antonella Contaldo, Francesco Paolo Bianchi, Giuseppe Losurdo, Andrea Iannone, Enzo Ierardi, Silvio Tafuri, Alfredo Di Leo, and IBD Endoscopy Team Work. 2020. "Inter-Observer Agreement of a New Endoscopic Score for Ulcerative Colitis Activity: Preliminary Experience" Diagnostics 10, no. 4: 213. https://doi.org/10.3390/diagnostics10040213

APA Style

Principi, M., Contaldo, A., Bianchi, F. P., Losurdo, G., Iannone, A., Ierardi, E., Tafuri, S., Di Leo, A., & IBD Endoscopy Team Work. (2020). Inter-Observer Agreement of a New Endoscopic Score for Ulcerative Colitis Activity: Preliminary Experience. Diagnostics, 10(4), 213. https://doi.org/10.3390/diagnostics10040213

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop