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Polymers, Volume 8, Issue 6

June 2016 - 37 articles

Cover Story: A pH-responsive theranostic agent based on core cross-linked (CCL) micelles was constructed via thiol–epoxy click chemistry between thiol-terminated tetraphenylethylene derivatives (TPE-4SH) and glycidyl moieties. The resulting CCL micelles were further functionalized: A targeting motif, pH low insertion peptide (pHLIP), and a magnetic resonance (MR) contrast agent were loaded with chemotherapeutic camptothecin (CPT). The as-prepared theranostic vector was efficiently taken up by taking advantage of the pHLIP-facilitated internalization that can be facilely traced by TPE fluorescence and MR imaging. Selective intracellular CPT release was accomplished, due to a hydrophobic-to-hydrophilic transition of micelle cores within acidic organelles. By Jinming Hu. View this paper.
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Articles (37)

  • Article
  • Open Access
18 Citations
8,294 Views
32 Pages

Multiphasic Reaction Modeling for Polypropylene Production in a Pilot-Scale Catalytic Reactor

  • Mohammad Jakir Hossain Khan,
  • Mohd Azlan Hussain and
  • Iqbal Mohammed Mujtaba

14 June 2016

In this study, a novel multiphasic model for the calculation of the polypropylene production in a complicated hydrodynamic and the physiochemical environments has been formulated, confirmed and validated. This is a first research attempt that describ...

  • Review
  • Open Access
43 Citations
15,677 Views
25 Pages

Polyglycidol, Its Derivatives, and Polyglycidol-Containing Copolymers—Synthesis and Medical Applications

  • Mateusz Gosecki,
  • Mariusz Gadzinowski,
  • Monika Gosecka,
  • Teresa Basinska and
  • Stanislaw Slomkowski

9 June 2016

Polyglycidol (or polyglycerol) is a biocompatible polymer with a main chain structure similar to that of poly(ethylene oxide) but with a –CH2OH reactive side group in every structural unit. The hydroxyl groups in polyglycidol not only increase the hy...

  • Article
  • Open Access
12 Citations
6,815 Views
19 Pages

SANS from Salt-Free Aqueous Solutions of Hydrophilic and Highly Charged Star-Branched Polyelectrolytes

  • François Boué,
  • Jérôme Combet,
  • Bruno Demé,
  • Martine Heinrich,
  • Jean-Georges Zilliox and
  • Michel Rawiso

8 June 2016

Scattering functions of sodium sulfonated polystyrene (NaPSS) star-branched polyelectrolytes with high sulfonation degrees were measured from their salt-free aqueous solutions, using the Small Angle Neutron Scattering (SANS) technique. Whatever the c...

  • Article
  • Open Access
23 Citations
7,896 Views
20 Pages

8 June 2016

Flow induced crystallization of semi-crystalline polymers is an important issue in polymer science and engineering because the changes in morphology strongly affect the properties of polymer materials. In this study, a phase field technique consideri...

  • Article
  • Open Access
8 Citations
6,388 Views
9 Pages

Production and Characterization of a Novel, Electrospun, Tri-Layer Polycaprolactone Membrane for the Segregated Co-Culture of Bone and Soft Tissue

  • Sasima Puwanun,
  • Frazer J. Bye,
  • Moira M. Ireland,
  • Sheila MacNeil,
  • Gwendolen C. Reilly and
  • Nicola H. Green

7 June 2016

Composite tissue-engineered constructs combining bone and soft tissue have applications in regenerative medicine, particularly dentistry. This study generated a tri-layer, electrospun, poly-ε-caprolactone membrane, with two microfiber layers separate...

  • Article
  • Open Access
26 Citations
10,018 Views
19 Pages

High Temperature Epoxy Foam: Optimization of Process Parameters

  • Samira El Gazzani,
  • Valérie Nassiet,
  • Jean-Pierre Habas,
  • Christian Freydier and
  • Aline Hilleshein

7 June 2016

For many years, reduction of fuel consumption has been a major aim in terms of both costs and environmental concerns. One option is to reduce the weight of fuel consumers. For this purpose, the use of a lightweight material based on rigid foams is a...

  • Review
  • Open Access
84 Citations
15,821 Views
20 Pages

7 June 2016

The organic/inorganic hybrid materials from polyhedral oligomeric silsesquioxane (POSS, inorganic nanoparticles) and polybenzoxazine (PBZ) have received much interesting recently due to their excellent thermal and mechanical properties, flame retarda...

  • Article
  • Open Access
19 Citations
10,848 Views
17 Pages

7 June 2016

The development of novel theranostic nanovectors is of particular interest in treating formidable diseases (e.g., cancers). Herein, we report a new tumor-targetable theranostic agent based on core crosslinked (CCL) micelles, possessing tumor targetab...

  • Article
  • Open Access
27 Citations
5,968 Views
11 Pages

7 June 2016

Mass transfer restrictions of scaffolds are currently hindering the development of three-dimensional (3D), clinically viable, and tissue-engineered constructs. For this situation, a 3D poly(lactide-co-glycolide)/hydroxyapatite porous scaffold, which...

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Polymers - ISSN 2073-4360