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Toxins, Volume 4, Issue 5

May 2012 - 6 articles

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Articles (6)

  • Article
  • Open Access
11 Citations
8,182 Views
17 Pages

24 May 2012

On the market since 1996, genetically modified plants expressing an insecticidal toxin (Cry toxin stemmed from Bacillus thuringiensis) target several lepidopteran and coleopteran pests. In this study, we assessed the impact of two varieties of Bt mai...

  • Review
  • Open Access
34 Citations
8,627 Views
9 Pages

Control of Ochratoxin A Production in Grapes

  • María Lorena Ponsone,
  • María Laura Chiotta,
  • Juan Manuel Palazzini,
  • Mariana Combina and
  • Sofía Chulze

14 May 2012

Ochratoxin A (OTA) is a mycotoxin commonly present in cereals, grapes, coffee, spices, and cocoa. Even though the main objective of the food and feed chain processors and distributors is to avoid the extended contamination of plant-derived foods and...

  • Article
  • Open Access
19 Citations
7,661 Views
11 Pages

Dimethylarginine Dimethylaminohydrolase/Nitric Oxide Synthase Pathway in Liver and Kidney: Protective Effect of Cyanidin 3-O-β-D-Glucoside on Ochratoxin-A Toxicity

  • Valeria Sorrenti,
  • Claudia Di Giacomo,
  • Rosaria Acquaviva,
  • Matteo Bognanno,
  • Ester Grilli,
  • Nicolantonio D’Orazio and
  • Fabio Galvano

8 May 2012

The aim of the present study was to evaluate the effect of long-term cyanidin 3-O-β-D-glucoside (C3G) and/or Ochratoxin A (OTA)-exposure on dimethylarginine dimethylamino hydrolase/nitric oxide synthase (DDAH/NOS) pathway in rats. The experiments wer...

  • Article
  • Open Access
41 Citations
9,084 Views
16 Pages

Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge Halichondria okadai

  • Ryo Matsumoto,
  • Yuki Fujii,
  • Sarkar M. A. Kawsar,
  • Robert A. Kanaly,
  • Hidetaro Yasumitsu,
  • Yasuhiro Koide,
  • Imtiaj Hasan,
  • Chihiro Iwahara,
  • Yukiko Ogawa and
  • Chang Hun Im
  • + 6 authors

30 April 2012

A divalent cation-independent lectin—HOL-18, with cytotoxic activity against leukemia cells, was purified from a demosponge, Halichondria okadai. HOL-18 is a 72 kDa tetrameric lectin that consists of four non-covalently bonded 18 kDa subunits. Hemagg...

  • Article
  • Open Access
32 Citations
6,646 Views
14 Pages

Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic Acid Toxins

  • Henry G. F. Smienk,
  • Dolores Calvo,
  • Pedro Razquin,
  • Elena Domínguez and
  • Luis Mata

30 April 2012

A phosphatase inhibition assay for detection of okadaic acid (OA) toxins in shellfish, OkaTest, was single laboratory validated according to international recognized guidelines (AOAC, EURACHEM). Special emphasis was placed on the ruggedness of the me...

  • Review
  • Open Access
36 Citations
9,229 Views
27 Pages

Disintegrins from Hematophagous Sources

  • Teresa C. F. Assumpcao,
  • José M. C. Ribeiro and
  • Ivo M. B. Francischetti

26 April 2012

Bloodsucking arthropods are a rich source of salivary molecules (sialogenins) which inhibit platelet aggregation, neutrophil function and angiogenesis. Here we review the literature on salivary disintegrins and their targets. Disintegrins were first...

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Toxins - ISSN 2072-6651