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Toxins, Volume 13, Issue 10

October 2021 - 65 articles

Cover Story: The toxicokinetics of the food and feed contaminant Fumonisin B1 (FB1) are characterized by low oral absorption and rapid plasma elimination. For these reasons, FB1 is not considered to accumulate in animals. This study shows for the first time that FB1 accumulates in liver and muscle after four and nine days of exposure of chickens to a non-toxic dose of around 20 mg FB1 + FB2/kg of feed. Concentrations of sphinganine (Sa) and sphingosine (So) increased over time in the liver, but no sign of toxicity and no effect on performances were observed. Feeding algo-clay to the chickens reduced accumulation of FB1 in the liver and muscle approximately 40% and 50%, respectively, on day nine, and decreased Sa and So contents in the liver compared to the levels of Sa and So found in chickens fed FB1 alone. View this paper
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Articles (65)

  • Article
  • Open Access
9 Citations
3,762 Views
25 Pages

Prioritization of Mycotoxins Based on Their Genotoxic Potential with an In Silico-In Vitro Strategy

  • Maria Alonso-Jauregui,
  • María Font,
  • Elena González-Peñas,
  • Adela López de Cerain and
  • Ariane Vettorazzi

19 October 2021

Humans are widely exposed to a great variety of mycotoxins and their mixtures. Therefore, it is important to design strategies that allow prioritizing mycotoxins based on their toxic potential in a time and cost-effective manner. A strategy combining...

  • Article
  • Open Access
5 Citations
3,015 Views
12 Pages

Evaluation of Cyanobacterial Bloom from Lake Taihu as a Protein Substitute in Fish Diet—A Case Study on Tilapia

  • Yan Huo,
  • Yuanze Li,
  • Wei Guo,
  • Jin Liu,
  • Cuiping Yang,
  • Lin Li,
  • Haokun Liu and
  • Lirong Song

19 October 2021

The utility of cyanobacterial bloom is often hindered by concerns about the toxin content. Over three years of investigation, we found that the toxin content of cyanobacterial bloom in Lake Taihu was always low in June and higher in late summer and a...

  • Article
  • Open Access
11 Citations
6,933 Views
14 Pages

19 October 2021

This study explored and investigated how zearalenone (ZEA) affects the morphology of small intestine and the distribution and expression of ghrelin and proliferating cell nuclear antigen (PCNA) in the small intestine of weaned gilts. A total of 20 we...

  • Article
  • Open Access
10 Citations
3,930 Views
13 Pages

Passage Number-Induced Replicative Senescence Modulates the Endothelial Cell Response to Protein-Bound Uremic Toxins

  • Fatima Guerrero,
  • Andres Carmona,
  • Maria Jose Jimenez,
  • Teresa Obrero,
  • Victoria Pulido,
  • Juan Antonio Moreno,
  • Sagrario Soriano,
  • Alejandro Martín-Malo and
  • Pedro Aljama

19 October 2021

Endothelial aging may be induced early in pathological situations. The uremic toxins indoxyl sulfate (IS) and p-cresol (PC) accumulate in the plasma of chronic kidney disease (CKD) patients, causing accelerated endothelial aging, increased cardiovasc...

  • Article
  • Open Access
32 Citations
4,504 Views
13 Pages

18 October 2021

Salinity is an important factor for regulating metabolic processes in aquatic organisms; however, its effects on toxicity and STX biosynthesis gene responses in dinoflagellates require further elucidation. Herein, we evaluated the physiological respo...

  • Article
  • Open Access
21 Citations
4,251 Views
15 Pages

The Protective Effect of Heme Oxygenase-1 on Liver Injury Caused by DON-Induced Oxidative Stress and Cytotoxicity

  • Zitong Meng,
  • Liangliang Wang,
  • Yuxiao Liao,
  • Zhao Peng,
  • Dan Li,
  • Xiaolei Zhou,
  • Shuang Liu,
  • Yanmei Li,
  • Andreas K. Nüssler and
  • Liegang Liu
  • + 2 authors

17 October 2021

Deoxynivalenol (DON) is a kind of Fusarium toxin that can cause a variety of toxic effects. Oxidative stress and DNA damage play a critical role in the toxicity of DON. However, previous studies focused more on acute toxicity in vivo/vitro models and...

  • Article
  • Open Access
5 Citations
4,485 Views
11 Pages

Tetrodotoxin/Saxitoxins Selectivity of the Euryhaline Freshwater Pufferfish Dichotomyctere fluviatilis

  • Hongchen Zhu,
  • Towa Sakai,
  • Yuji Nagashima,
  • Hiroyuki Doi,
  • Tomohiro Takatani and
  • Osamu Arakawa

16 October 2021

The present study evaluated differences in the tetrodotoxin (TTX)/saxitoxins (STXs) selectivity between marine and freshwater pufferfish by performing in vivo and in vitro experiments. In the in vivo experiment, artificially reared nontoxic euryhalin...

  • Article
  • Open Access
23 Citations
4,277 Views
19 Pages

Effects of Deoxynivalenol and Fumonisins on Broiler Gut Cytoprotective Capacity

  • Vasileios Paraskeuas,
  • Eirini Griela,
  • Dimitrios Bouziotis,
  • Konstantinos Fegeros,
  • Gunther Antonissen and
  • Konstantinos C. Mountzouris

16 October 2021

Mycotoxins are a crucial problem for poultry production worldwide. Two of the most frequently found mycotoxins in feedstuffs are deoxynivalenol (DON) and fumonisins (FUM) which adversely affect gut health and poultry performance. The current knowledg...

  • Article
  • Open Access
11 Citations
4,051 Views
12 Pages

Occurrence and Characterization of Penicillium Species Isolated from Post-Harvest Apples in Lebanon

  • Wassim Habib,
  • Mario Masiello,
  • Hala Chahine-Tsouvalakis,
  • Zahraa Al Moussawi,
  • Carine Saab,
  • Salwa Tohmé Tawk,
  • Luca Piemontese,
  • Michele Solfrizzo,
  • Antonio Francesco Logrieco and
  • Antonio Moretti
  • + 1 author

16 October 2021

The apple is one of the most important fruit tree crops in the Mediterranean region. Lebanon, in particular, is among the top apple producer countries in the Middle East; however, recently, several types of damage, particularly rot symptoms, have bee...

  • Article
  • Open Access
17 Citations
3,757 Views
17 Pages

Enniatin B and Deoxynivalenol Activity on Bread Wheat and on Fusarium Species Development

  • Luisa Ederli,
  • Giovanni Beccari,
  • Francesco Tini,
  • Irene Bergamini,
  • Ilaria Bellezza,
  • Roberto Romani and
  • Lorenzo Covarelli

15 October 2021

Fusarium head blight (FHB) is a devastating wheat disease, mainly caused by Fusarium graminearum (FG)—a deoxynivalenol (DON)-producing species. However, Fusarium avenaceum (FA), able to biosynthesize enniatins (ENNs), has recently increased its relev...

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Toxins - ISSN 2072-6651Creative Common CC BY license