Table of Contents
Toxins, Volume 11, Issue 9 (September 2019) – 67 articles
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Cover Story (view full-size image) Animal venoms, especially from spiders, are among the most promising sources of novel drug leads. [...] Read more. Animal venoms, especially from spiders, are among the most promising sources of novel drug leads. However, the bioprospecting strategies for venoms need to be optimized in order to facilitate their economic implementation. In our study, we used the plethora of deposited tarantula toxins from public databases in tandem with published phylogenetic data to unravel understudied genetic lineages within the family and to determine priority groups for future bioprospecting studies. This rational taxon selection based on evolutionary relationships may be applied to other, likewise biodiverse yet venom-wise understudied taxa and could be helpful to economize and optimize venom bioprospecting across the metazoan tree of life. View this paper