The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
by
Qingtao Hou 1,†, Yun Li 2,†, Ling Li 3, Gaiping Cheng 4, Xin Sun 3, Sheyu Li 1,*
and Haoming Tian 1,*
Qingtao Hou 1,†, Yun Li 2,†, Ling Li 3, Gaiping Cheng 4, Xin Sun 3, Sheyu Li 1,* and Haoming Tian 1,*
1
Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China
2
Department of Endocrinology and Metabolism, The Third People’s Hospital of Chengdu, Chengdu 610031, China
3
Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China
4
Department of Clinical Nutrition, West China Hospital, Sichuan University, Chengdu 610041, China
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Nutrients 2015, 7(12), 10369-10387; https://doi.org/10.3390/nu7125536
Received: 29 September 2015 / Revised: 11 November 2015 / Accepted: 26 November 2015 / Published: 10 December 2015
The present study aimed to comprehensively assess if oats intake is beneficial for diabetic patients. The literature search was conducted in PubMed database up to 23 August 2015. Fourteen controlled trials and two uncontrolled observational studies were included. Compared with the controls, oats intake significantly reduced the concentrations of glycosylated hemoglobin A1c (HbA1c) (MD, −0.42%; 95% CI, −0.61% to −0.23%), fasting blood glucose (FBG) (MD, −0.39 mmol/L; 95% CI, −0.58 to −0.19 mmol/L), total cholesterol (TC) (MD, −0.49 mmol/L; 95% CI, −0.86 to −0.12 mmol/L), low-density lipoprotein cholesterol (LDL-C) (MD, −0.29 mmol/L; 95% CI, −0.48 to −0.09 mmol/L). Oatmeal significantly reduced the acute postprandial glucose and insulin responses compared with the control meal. The present study has revealed a beneficial effect of oats intake on glucose control and lipid profiles in type 2 diabetic patients. Further investigations of oats intake in patients with type 1 diabetes and the safety of oats consumption are required.
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Keywords:
oats; β-glucan; type 2 diabetes mellitus; glycemic control; cholesterol; systematic review; meta-analysis
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MDPI and ACS Style
Hou, Q.; Li, Y.; Li, L.; Cheng, G.; Sun, X.; Li, S.; Tian, H. The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis. Nutrients 2015, 7, 10369-10387.
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