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Intake of Tibetan Hull-Less Barley is Associated with a Reduced Risk of Metabolic Related Syndrome in Rats Fed High-Fat-Sucrose Diets

by Lingxiao Gong 1,†, Lingyun Gong 2,† and Ying Zhang 1,*
1
Department of Food Science and Nutrition, College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China
2
Department of Neurology, Huashan Hospital, Jingan 200040, Shanghai, China
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work and should be considered co-first authors.
Nutrients 2014, 6(4), 1635-1648; https://doi.org/10.3390/nu6041635
Received: 30 December 2013 / Revised: 2 April 2014 / Accepted: 2 April 2014 / Published: 21 April 2014
The objective of this study was to assess the effects of whole grain Tibetan hull-less barley on metabolic related syndrome induced by high-fat-sucrose diets in rats. The diets were designed to reflect the dietary patterns of Chinese individuals (>30% energy fat) with refined wheat flour (HFS-W) or Tibetan hull-less barley (HFS-THB) as the main carbohydrate sources. Rats fed HFS-W had increased body weight, abdominal fat deposition, liver weight, liver fat deposition, triglyceride (TG), fasting blood glucose (FBG), serum fasting insulin (FINS), and homeostasis model assessment of insulin resistance (HOMA-IR) scores, and decreased low-density lipoprotein cholesterol (LDL-C) levels compared to rats fed a basal diet (BD). However, rats fed HFS-THB had reduced body weight gain, dyslipidemia, and insulin resistance. These findings indicate that whole Tibetan hull-less barley is a functional food that can reduce the prevalence of metabolic related syndrome induced by high-fat-sucrose diets. View Full-Text
Keywords: Tibetan hull-less barley (THB); whole grain; metabolic related syndrome; insulin resistance Tibetan hull-less barley (THB); whole grain; metabolic related syndrome; insulin resistance
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Gong, L.; Gong, L.; Zhang, Y. Intake of Tibetan Hull-Less Barley is Associated with a Reduced Risk of Metabolic Related Syndrome in Rats Fed High-Fat-Sucrose Diets. Nutrients 2014, 6, 1635-1648.

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