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  • Correction
  • Open Access

27 March 2026

4 Pages

Correction: Pedersen et al. A Guinea Pig Model of Pediatric Metabolic Dysfunction-Associated Steatohepatitis: Poor Vitamin C Status May Advance Disease. Nutrients 2025, 17, 291

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1
Section of Preclinical Disease Biology, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark
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Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA
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Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen, Denmark
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Institut de Pharmacologie Moléculaire et Cellulaire, CNRS and Université de Nice Côte d’Azur, 06560 Valbonne, France

Error in Table

In the original publication [1], there was a mistake in Table 2 as published. Plasma total cholesterol (TC) values were mistakenly reported as log-transformed data. The corrected values are:
HFHC: 6.51 (3.60–8.71) [initially and faulty reported as 0.81 (0.56–0.94)]
HFLC: 8.88 (5.52–12.09) [initially and faulty reported as 0.95 (0.74–1.08)]
The corrected Table 2 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Table 2. Plasma and liver biochemistry.

Error in Figure and Legend

In the original publication, there was a mistake in the figure and legend for Figure 3. The figure and legend indicate fibrosis fraction as a percentage (%) and should only be fraction. The portal inflammation scale was misstated as 0–1 in the legend and should be corrected to 0–2. The correct Figure 3 and legend appear below. The authors state that the scientific conclusions are unaffected.
Figure 3. Histopathological scoring and fibrosis quantification. All data except steatosis location are presented as individual scores with medians. (a) Steatosis scores on a scale of 0–3, (b) prevalence of different steatosis locations, (c) lobular inflammation scores on a scale of 0–3, (d) portal inflammation scores on a scale of 0–2, (e) ballooning scores on a scale of 0–2, (f) MASLD/NAFLD activity scores (NAS) on a scale of 0–8, (g) fibrosis scores on a scale of 0–4, (h) fibrosis fractions. Histopathological scoring data were analyzed with non-parametric Kruskal–Wallis’ test and Dunn’s test for multiple comparisons. Fibrosis fractions were log-transformed and analyzed via two-way ANOVA. *** p < 0.001, **** p < 0.0001, ns: not statistically significant. LFHC: low-fat high-VitC, LFLC: low-fat low-VitC, HFHC: high-fat high-VitC, HFLC: high-fat low-VitC.

Reference

  1. Pedersen, K.; Poojari, A.; Colberg, S.F.; Mechernsee, S.M.; Iversen, J.F.; Barrès, R.; Lykkesfeldt, J.; Tveden-Nyborg, P. A Guinea Pig Model of Pediatric Metabolic Dysfunction-Associated Steatohepatitis: Poor Vitamin C Status May Advance Disease. Nutrients 2025, 17, 291. [Google Scholar] [CrossRef] [Scilit] [PubMed]
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