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25 March 2013

Invasive Pneumococcal Infection Despite 7-Valent Conjugated Vaccine

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1
Department of Pediatrics, University Hospital of Lausanne (CHUV), Switzerland
2
Pediatric Intensive Care Unit, University Hospital of Lausanne (CHUV), Switzerland
*
Author to whom correspondence should be addressed.

Abstract

Despite good cover with 7-valent vaccination, invasive pneumococcal infections may still be misdiagnosed and may lead to lifethreatening situations or death in young children. New serotypes are emerging and, therefore, clinicians must keep a high level of suspicion in young children regardless of their vaccination status. We report three cases of invasive pneumococcal infection due to new serotypes not covered by the 7-valent conjugated vaccine, two of which led children to death.

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