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Journal of Xenobiotics, Volume 15, Issue 1

February 2025 - 33 articles

Cover Story: Models for NOEL (No Observed Effect Level) and NOEC (No Observed Effect Concentration) related to the long-term/reproduction toxicity of various organic pesticides are built up, evaluated, and compared with similar models proposed in the literature. The data have been obtained from the EFSA OpenFoodTox database, collecting only data for the Bobwhite quail (Colinus virginianus). Models have been developed using the CORAL program, which can be used to develop quantitative structure-property/activity relationships (QSPRs/QSARs), and the Monte Carlo method for the optimization of the model. The software provided a model which may be considered useful for the practice. The determination coefficient of the best models for the external validation set was 0.665. View this paper
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Articles (33)

  • Review
  • Open Access
22 Citations
7,909 Views
31 Pages

Endocrine Disrupting Toxicity of Bisphenol A and Its Analogs: Implications in the Neuro-Immune Milieu

  • Erica Buoso,
  • Mirco Masi,
  • Roberta Valeria Limosani,
  • Chiara Oliviero,
  • Sabrina Saeed,
  • Martina Iulini,
  • Francesca Carlotta Passoni,
  • Marco Racchi and
  • Emanuela Corsini

17 January 2025

Endocrine-disrupting chemicals (EDCs) are natural or synthetic substances that are able to interfere with hormonal systems and alter their physiological signaling. EDCs have been recognized as a public health issue due to their widespread use, enviro...

  • Article
  • Open Access
3 Citations
2,186 Views
14 Pages

16 January 2025

Chlorpyrifos (CPF) is a broad-spectrum organophosphate insecticide. Long-term exposure to low levels of CPF is associated with neurodevelopmental and neurodegenerative disorders. The mechanisms leading to these effects are still not fully understood....

  • Article
  • Open Access
2 Citations
1,811 Views
23 Pages

Assessing Variability in Children’s Exposure to Contaminants in Food: A Longitudinal Non-Targeted Analysis Study in Miami, Florida

  • Luciana Teresa Dias Cappelini,
  • Olutobi Daniel Ogunbiyi,
  • Vinícius Guimarães Ferreira,
  • Mymuna Monem,
  • Carolina Cuchimaque Lugo,
  • Monica Beatriz Perez,
  • Piero Gardinali,
  • Florence George,
  • Daniel M. Bagner and
  • Natalia Quinete

14 January 2025

Food is essential for human survival; however, food can be an important route of exposure to contaminants. This study investigated the presence and distribution of anthropogenic contaminants in food consumed by families with small children in South F...

  • Article
  • Open Access
2 Citations
1,372 Views
14 Pages

10 January 2025

Nanoplastics pose a growing threat to marine ecosystems, particularly affecting the early developmental stages of marine organisms. This study investigates the effects of amino-modified polystyrene nanoparticles (PS-NH2, 50 nm) on the embryonic devel...

  • Review
  • Open Access
4,331 Views
22 Pages

Cardiotoxicity of Chemotherapy: A Multi-OMIC Perspective

  • Yan Ma,
  • Mandy O. J. Grootaert and
  • Raj N. Sewduth

8 January 2025

Chemotherapy-induced cardiotoxicity is a critical issue in cardio-oncology, as cancer treatments often lead to severe cardiovascular complications. Approximately 10% of cancer patients succumb to cardiovascular problems, with lung cancer patients fre...

  • Article
  • Open Access
1 Citations
3,135 Views
12 Pages

Reducing the Formation of Toxic Byproducts During the Photochemical Release of Epinephrine

  • Mikhail A. Panfilov,
  • Ezhena S. Starodubtseva,
  • Tatyana Yu. Karogodina,
  • Alexey Yu. Vorob’ev and
  • Alexander E. Moskalensky

8 January 2025

Engineered light-sensitive molecules offer a sophisticated toolkit for the manipulation of biological systems with both spatial and temporal precision. Notably, artificial “caged” compounds can activate specific receptors solely in respon...

  • Article
  • Open Access
2 Citations
2,372 Views
21 Pages

7 January 2025

Background: Chronic stress, characterized by sustained activation of physiological stress response systems, is a key risk factor for numerous health conditions. Allostatic load (AL), a biomarker of cumulative physiological stress, offers a quantitati...

  • Review
  • Open Access
20 Citations
13,061 Views
26 Pages

31 December 2024

Skin represents an effective barrier against the penetration of external agents into the human body. Nevertheless, recent research has shown that small particles, especially in the nanosized range, can not only penetrate through the skin but also wor...

  • Article
  • Open Access
2 Citations
2,003 Views
20 Pages

31 December 2024

Ibuprofen (IBP) is one of the most consumed drugs in the world. It is only partially removed in wastewater treatment plants (WWTPs), being present in effluent wastewater and sewage sludge, causing the widespread introduction of IBP as an emergent xen...

  • Article
  • Open Access
3 Citations
1,274 Views
15 Pages

Residual Dynamics of Chlorantraniliprole and Fludioxonil in Soil and Their Effects on the Microbiome

  • Nan Hao,
  • Huimin Zhang,
  • Hui Jia,
  • Yuwei Zhao,
  • Jiaqi Li,
  • Xiaoxiao Feng,
  • Bowen Tang,
  • Bin Zhao and
  • Yingchao Liu

30 December 2024

The increased use of chlorantraniliprole and fludioxonil has sparked concerns about their residues and impact on the soil microbiome, highlighting an urgent issue requiring attention. This study investigates the residue dynamics of corn after chloran...

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J. Xenobiot. - ISSN 2039-4713