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Journal of Xenobiotics, Volume 15, Issue 1

February 2025 - 33 articles

Cover Story: Models for NOEL (No Observed Effect Level) and NOEC (No Observed Effect Concentration) related to the long-term/reproduction toxicity of various organic pesticides are built up, evaluated, and compared with similar models proposed in the literature. The data have been obtained from the EFSA OpenFoodTox database, collecting only data for the Bobwhite quail (Colinus virginianus). Models have been developed using the CORAL program, which can be used to develop quantitative structure-property/activity relationships (QSPRs/QSARs), and the Monte Carlo method for the optimization of the model. The software provided a model which may be considered useful for the practice. The determination coefficient of the best models for the external validation set was 0.665. View this paper

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Article

2 Citations

1,537 Views

15 Pages

Simulation of the Long-Term Toxicity Towards Bobwhite Quail (Colinus virginianus) by the Monte Carlo Method

Nadia Iovine,
Alla P. Toropova,
Andrey A. Toropov,
Alessandra Roncaglioni and
Emilio Benfenati

J. Xenobiot.2025, 15(1), 3;https://doi.org/10.3390/jox15010003

26 December 2024

In this study, models for NOEL (No Observed Effect Level) and NOEC (No Observed Effect Concentration) related to long-term/reproduction toxicity of various organic pesticides are built up, evaluated, and compared with similar models proposed in the l...

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Article

3 Citations

1,616 Views

20 Pages

Impact of Short-Chain Perfluoropropylene Oxide Acids on Biochemical and Behavioural Parameters in Eisenia fetida (Savigny, 1826)

Davide Rotondo,
Davide Gualandris,
Candida Lorusso,
Albert Braeuning,
Antonio Calisi and
Francesco Dondero

J. Xenobiot.2025, 15(1), 2;https://doi.org/10.3390/jox15010002

26 December 2024

Per- and polyfluoroalkyl substances (PFAS) are a class of persistent organic pollutants that pose a growing threat to environmental and human health. Soil acts as a long-term reservoir for PFAS, potentially impacting soil biodiversity and ecosystem f...

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Review

11 Citations

5,270 Views

30 Pages

Epigenetic Mechanisms of Endocrine-Disrupting Chemicals in Breast Cancer and Their Impact on Dietary Intake

Desh Deepak Singh

J. Xenobiot.2025, 15(1), 1;https://doi.org/10.3390/jox15010001

24 December 2024

Addressing the consequences of exposure to endocrine-disrupting chemicals (EDCs) demands thorough research and elucidation of the mechanism by which EDCs negatively impact women and lead to breast cancer (BC). Endocrine disruptors can affect major pa...

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J. Xenobiot. - ISSN 2039-4713

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