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Thalassemia Reports, Volume 15, Issue 1

March 2025 - 3 articles

Cover Story: Acute transfusion reactions are transfusion-related events that can significantly affect patient safety and therapeutic management. APTRs pose a significant challenge in transfusion medicine, requiring a multifaceted approach to therapy and prevention. Through hemovigilance procedures, healthcare professionals can enhance patient outcomes and transfusion safety by fostering awareness, promoting research, improving surveillance and reporting mechanisms, and prioritizing patient education and follow-up care. Such efforts will deepen the understanding of APTRs and support the development of more effective strategies for their management and prevention. View this paper
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Articles (3)

  • Perspective
  • Open Access
1,578 Views
6 Pages

Thalassemia and sickle cell disease remain the most common life-threatening non-communicable diseases in children worldwide and an increasing burden on affected families and health services. Significant progress has been made in terms of technologies...

  • Review
  • Open Access
3,456 Views
10 Pages

New Perspectives on the Impact of Iron Chelation Therapy on the Gut Microbiome in Thalassemia Patients

  • Sara Deumić,
  • Neira Crnčević,
  • Mirsada Hukić,
  • Muamer Dizdar and
  • Monia Avdić

Thalassemia, a genetic condition characterized by defective hemoglobin synthesis, is often managed with transfusion therapy, which can lead to iron overload—a significant contributor to morbidity and mortality due to organ damage and pathogenic...

  • Review
  • Open Access
1 Citations
4,358 Views
8 Pages

Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management

  • Sophia Delicou,
  • Aspasia Argyrou,
  • Sophia Mellou,
  • Aikaterini Xydaki,
  • Anthippi Gafou and
  • Constantina Politis

It is important to recognize the significance of acute painful transfusion reactions (APTRs) as a complication of blood transfusions. These adverse reactions are characterized by the onset of acute pain after the administration of blood components. D...

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Thalass. Rep. - ISSN 2039-4365