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Hematology Reports, Volume 17, Issue 6

December 2025 - 14 articles

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Articles (14)

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Review

729 Views

12 Pages

Navigating the New Era in Myelodysplastic Neoplasms: A Review of Prognostic Implications of the IPSS-M Score and 2022 WHO Classification

Mihai-Emilian Lapadat,
Oana Stanca,
Nicoleta Mariana Berbec,
Cristina Negotei and
Andrei Colita

Hematol. Rep.2025, 17(6), 58;https://doi.org/10.3390/hematolrep17060058

30 October 2025

Myelodysplastic neoplasms represent a diverse group of clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, peripheral cytopenias, and an inherent risk of progression to acute myeloid leukemia. Accurate risk assessment...

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Article

596 Views

10 Pages

Role of Daratumumab, Lenalidomide, and Dexamethasone in Transplantation-Eligible Patients with Multiple Myeloma After the Failure of Bortezomib-Based Induction Therapy

Shun Ito,
Takashi Hamada,
Masaru Nakagawa,
Takashi Ichinohe,
Hironao Nukariya,
Toshihide Endo,
Kazuya Kurihara,
Yuichi Takeuchi,
Shimon Otake and
Hiromichi Takahashi
+ 2 authors

Hematol. Rep.2025, 17(6), 57;https://doi.org/10.3390/hematolrep17060057

29 October 2025

Background/Objectives: The role of daratumumab, lenalidomide, and dexamethasone (DRd) in autologous stem cell transplantation (ASCT)-eligible patients with multiple myeloma (MM) after first-line bortezomib, cyclophosphamide, and dexamethasone (VCd) t...

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Review

1,207 Views

20 Pages

The Gut Microbiome Role in Multiple Myeloma: Emerging Insights and Therapeutic Opportunities

Mina Y. George,
Nada K. Gamal,
Daniel E. Mansour,
Ademola C. Famurewa,
Debalina Bose,
Peter A. Messiha and
Claudio Cerchione

Hematol. Rep.2025, 17(6), 56;https://doi.org/10.3390/hematolrep17060056

27 October 2025

Multiple myeloma is a hematological cancer depicted by the proliferation of plasma cells within the bone marrow, causing immune dysfunction and other abnormalities. The gut microbiome, the microbial community in the gastrointestinal tract, was found...

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Article

872 Views

14 Pages

Outcomes for Primary Central Nervous System Lymphoma from a Single Institution

Sruthi Dontu,
Jacob Boccucci,
Michael Chahin,
Amany Keruakous,
Anand Jillella,
Jorge Cortes,
Vamsi Kota,
Locke Bryan and
Ayushi Chauhan

Hematol. Rep.2025, 17(6), 55;https://doi.org/10.3390/hematolrep17060055

24 October 2025

Background: Primary central nervous lymphoma (PCNSL) is a rare, aggressive, non-Hodgkin’s lymphoma. Outcomes are poor with standard induction of high-dose methotrexate (HD-MTX)-based regimens and consolidation. We present retrospective data fro...

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