Transformation of Low-Grade Follicular Yymphoma with Partial Marginal Zone Differentiation: Two Cases

Karen Nalbandyan; Daniel Benharroch; Anna Gurevitch; Itai Levi

doi:10.4081/hr.2021.8896

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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.

Case Report

17 September 2021

Transformation of Low-Grade Follicular Yymphoma with Partial Marginal Zone Differentiation: Two Cases

and

Department of Pathology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410, Israel

Division of Hematology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410, Israel

Author to whom correspondence should be addressed.

Hematol. Rep.2021, 13(3), 8896;https://doi.org/10.4081/hr.2021.8896

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Abstract

Two cases of low-grade follicular lymphoma, with marginal zone differentiation and/or with high proliferation rate in one of them, are reported with transformation into high grade B-cell and B-lymphoblastic lymphomas. The contribution of these features to the transforming process, although previously described, is infrequent, and has not been deciphered to date.

Keywords:

follicular lymphoma; high proliferation index; high grade B-cell lymphoma; transformation

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