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  • Brief Report
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22 November 2011

3 Pages

Bosentan and Sildenafil in the Treatment of HIV-Associated Pulmonary Hypertension

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1
Second Infectious Diseases Unit, L. Spallanzani National Institute for Infectious Diseases, Rome, Italy
2
U.O. Diagnostica per Immagini, S. Camillo-Forlanini Hospital, Rome, Italy
3
III Cardiology Unit, S. Camillo-Forlanini Hospital, Rome, Italy
*
Author to whom correspondence should be addressed.

Abstract

We present the case of an HIV/HCV-coinfected patient with HIV-related pulmonary hypertension (HRPH) who experienced a good clinical and functional response to bosentan, with a subsequent switch to oral sildenafil due to increased transaminase levels. Bosentan resulted less handy in this case, probably due to both side effects and co-morbidities.

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