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Infectious Disease Reports
Volume 2
Issue 1
10.4081/idr.2010.1824
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Infectious Disease Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

Mortality in Hospitalized Older Adults Associated with Clostridium difficile Infection at a District Hospital

by
Johannis Andreas Karas
1,2,*,
Simon Bradshaw
2,
Wabas Mahmud
2 and
David A. Enoch
1
1
Clinical Microbiology & Public Health Laboratory, Health Protection Agency, Papworth Hospital, Cambridge, UK
2
Hinchingbrooke Hospital, Hinchingbrooke Health Care NHS Trust, Huntingdon, UK
*
Author to whom correspondence should be addressed.
Infect. Dis. Rep. 2010, 2(1), e8; https://doi.org/10.4081/idr.2010.1824
Submission received: 27 April 2010 / Revised: 4 June 2010 / Accepted: 4 June 2010 / Published: 21 June 2010

Abstract

Clostridium difficile is the most common cause of hospital acquired infectious diarrhea in the developed world and has re-emerged in recent years with apparent greater morbidity and mortality. Despite this, there is little recent published data from the UK concerning associated mortality. We performed a case control study at a UK district general hospital of 66 hospitalized patients over the age of 65 years with C. difficile infection compared to 3-5 controls matched for age, sex and minimum length of stay. We found a significant excess mortality of 11.5% at seven days, 26.2% at 30 days, 38.1% at 90 days and 41.4% at 180 days. C. difficile infection in hospitalized elderly patients may contribute to long-term mortality or be a marker of poor prognosis and cases may require more intensive long-term follow up to improve mortality.
Keywords: Clostridium difficile; mortality Clostridium difficile; mortality

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MDPI and ACS Style

Karas, J.A.; Bradshaw, S.; Mahmud, W.; Enoch, D.A. Mortality in Hospitalized Older Adults Associated with Clostridium difficile Infection at a District Hospital. Infect. Dis. Rep. 2010, 2, e8. https://doi.org/10.4081/idr.2010.1824

AMA Style

Karas JA, Bradshaw S, Mahmud W, Enoch DA. Mortality in Hospitalized Older Adults Associated with Clostridium difficile Infection at a District Hospital. Infectious Disease Reports. 2010; 2(1):e8. https://doi.org/10.4081/idr.2010.1824

Chicago/Turabian Style

Karas, Johannis Andreas, Simon Bradshaw, Wabas Mahmud, and David A. Enoch. 2010. "Mortality in Hospitalized Older Adults Associated with Clostridium difficile Infection at a District Hospital" Infectious Disease Reports 2, no. 1: e8. https://doi.org/10.4081/idr.2010.1824

APA Style

Karas, J. A., Bradshaw, S., Mahmud, W., & Enoch, D. A. (2010). Mortality in Hospitalized Older Adults Associated with Clostridium difficile Infection at a District Hospital. Infectious Disease Reports, 2(1), e8. https://doi.org/10.4081/idr.2010.1824

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