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Infectious Disease Reports, Volume 17, Issue 3

June 2025 - 34 articles

Cover Story: Enterovirus-D68 (EV-D68) and rhinoviruses significantly contribute to respiratory illnesses in children and can lead to severe lower respiratory tract infections. These viruses present a spectrum of clinical features, from asymptomatic infection to mild upper respiratory symptoms and severe lower respiratory tract involvement. No specific antiviral treatments are currently approved for EV-D68 and rhinovirus infections. While supportive care remains the mainstay of treatment, antiviral agents offer potential therapeutic options in the future. This review aims to consolidate current knowledge on the antiviral options under investigation. We conducted a comprehensive literature review, analyzing ongoing research into antiviral agents targeting EV-D68 and rhinovirus infections. View this paper
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Articles (34)

  • Case Report
  • Open Access
961 Views
12 Pages

Tropheryma whipplei and Giardia intestinalis Co-Infection: Metagenomic Analysis During Infection and the Recovery Follow-Up

  • Anna Anselmo,
  • Fabiana Rizzo,
  • Elena Gervasi,
  • Luca Corrent,
  • Andrea Ciammaruconi,
  • Silvia Fillo,
  • Antonella Fortunato,
  • Anna Maria Marella,
  • Silvia Costantini and
  • Luca Baldassari
  • + 2 authors

Background: Whipple’s disease (WD) is a rare infection caused by Tropheryma whipplei. Diagnosis is challenging and requires a combination of several data sets, such as patient history, clinical and laboratory investigations, and endoscopy with...

  • Review
  • Open Access
1 Citations
2,839 Views
22 Pages

Advances in the Treatment of Enterovirus-D68 and Rhinovirus Respiratory Infections

  • Vonintsoa L. Rahajamanana,
  • Mathieu Thériault,
  • Henintsoa Rabezanahary,
  • Yesmine G. Sahnoun,
  • Maria Christina Mallet,
  • Sandra Isabel,
  • Sylvie Trottier and
  • Mariana Baz

Background/Objectives: Enterovirus-D68 (EV-D68) and rhinoviruses are major contributors to respiratory illnesses in children, presenting a spectrum of clinical manifestations ranging from asymptomatic cases to severe lower respiratory tract infection...

  • Case Report
  • Open Access
1 Citations
970 Views
10 Pages

The Underestimated Threat—Mycobacterium Genavense Infection: A Case Report

  • Jannik Sonnenberg,
  • Gert Gabriels,
  • Ioana Diana Olaru,
  • Sebastian Mühl,
  • Julia Fischer,
  • Hermann Pavenstädt,
  • Jonel Trebicka,
  • Kai-Henrik Peiffer and
  • Phil-Robin Tepasse

Background/Objectives: Nontuberculous mycobacteria (NTM) represent a heterogeneous group of pathogens with increasing global prevalence and significant geographical variation in species distribution. NTM infections, often affecting immunocompromised...

  • Article
  • Open Access
1,038 Views
16 Pages

Background/Objectives: COVID-19 pandemic had a significant impact on endemic respiratory illnesses. Through behavioral changes in populations and government policy, mainly through non-pharmaceutical interventions (NPIs), Canada saw historic lows in t...

  • Case Report
  • Open Access
970 Views
10 Pages

Vasculonecrotic Reaction Caused by Mycobacterium Lepromatosis Infection—A Case Report of an HIV/Leprosy-Coinfected Patient

  • Fernando Amador-Lara,
  • Jorge L. Mayorga-Garibaldi,
  • Felipe J. Bustos-Rodríguez,
  • Luz A. González-Hernández,
  • Pedro Martínez-Ayala and
  • Jaime F. Andrade-Villanueva

Background: Vasculonecrotic reactions in leprosy are typically associated with type 2 reactions. Differentiating between necrotizing erythema nodosum leprosum (nENL) and Lucio’s phenomenon (LP) can be difficult, as overlapping clinical and hist...

  • Review
  • Open Access
851 Views
11 Pages

Spatial, Social and Serological Factors in the Prevalence and Risk of Leprosy in Areas of High Endemicity: An Integrative Review

  • Daniele dos Santos Lages,
  • Isabela Cristina Lana Maciel,
  • Sarah Lamas Vidal and
  • Francisco Carlos Félix Lana

Background/Objectives: Leprosy remains a global public health challenge, especially in hyperendemic areas, where spatial, socioeconomic and serological factors influence its persistence. In this study, an integrative review was carried out to analyze...

  • Systematic Review
  • Open Access
2 Citations
5,262 Views
24 Pages

Background: Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, long COVID (LC) has become a significant global health burden. While knowledge about LC is accumulating, studies on its prevention are s...

  • Systematic Review
  • Open Access
954 Views
12 Pages

The Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker of Fournier’s Gangrene Severity: A Meta-Analysis

  • Konstantinos Seretis,
  • Nikolaos Bounas,
  • Konstantinos Sfaelos,
  • Georgios Gaitanis and
  • Ioannis Bassukas

Background/Objectives: Fournier’s Gangrene (FG) is a severe and potentially fatal necrotizing infection of the perianal and genital regions, which necessitates prompt therapeutic interventions to prevent disease progression. Accruing evidence f...

  • Article
  • Open Access
868 Views
13 Pages

The PJI-TNM Classification as Predictor for Revision-Free Implant Survival Rates in Patients with Periprosthetic Joint Infection of the Hip or Knee Joint

  • Frank Sebastian Fröschen,
  • Lisa Greber,
  • Ernst Molitor,
  • Gunnar Thorben Rembert Hischebeth,
  • Alexander Franz and
  • Thomas Martin Randau

Background: Periprosthetic joint infections (PJIs) remain a major challenge in arthroplasty. This study tries to evaluate the PJI-TNM classification as predictor for the revision-free implant survival in patients with PJI of the hip or knee joint. Me...

  • Case Report
  • Open Access
1 Citations
1,242 Views
9 Pages

A Case of Pulmonary Fibrosis and COVID-19-Related Pneumonia in a Pembrolizumab-Treated Patient

  • Alberto Zolezzi,
  • Gina Gualano,
  • Annelisa Mastrobattista,
  • Pietro Vittozzi,
  • Virginia Di Bari,
  • Carlotta Cerva,
  • Silvia Mosti,
  • Antonio Lugini,
  • Fabrizio Albarello and
  • Federica Di Stefano
  • + 2 authors

Pembrolizumab is used as a first-line treatment of non-small cell lung cancer. Pneumonitis and interstitial lung disease are among the most common immune-related adverse events. The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-...

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Infect. Dis. Rep. - ISSN 2036-7449