Special Issue "Mathematical Modeling of Viral Infection"

A special issue of Viruses (ISSN 1999-4915).

Deadline for manuscript submissions: 1 December 2020.

Special Issue Editors

Dr. Amber M. Smith
Guest Editor
University of Tennessee Health Science Center, Memphis, TN 38163, USA
Interests: respiratory infectious diseases; host–pathogen interaction; multi-pathogen infections; model prediction validation; parameter estimation
Dr. Ruian Ke
Guest Editor
Los Alamos National Laboratory, NM 87545, USA
Interests: multiscale modeling of viral and immune dynamics; treatment strategies for viral infections; HIV; HCV; influenza

Special Issue Information

Dear Colleagues,

The dynamics of virus infections are complex and multifaceted, and include the mechanisms by which a virus replicates, spreads within a host, interacts with host immune responses and with other pathogens, and the extent to which the virus can be targeted by or employed as therapeutic agent. Mathematical models are essential tools that provide a quantitative understanding of viral infections and their strategies, which are often difficult to dissect through only clinical or experimental approaches. The tight and improved integration of data within modeling frameworks has enhanced the predictive capability of these models and led to new experimental and clinical designs that have led to further elucidations of complex biological interplay. In addition, recent innovations in experimental biology and a new appreciation for multiparameter quantitative datasets have enhanced model quality and provided new questions ripe for mathematical approaches.

In this Special Issue, we will showcase recent advancements in mathematical modeling of virus infections. We welcome submissions reporting any aspect of modeling virus infections.

Dr. Amber M. Smith
Dr. Ruian Ke
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • viral dynamics
  • host-pathogen interaction
  • immune response
  • coinfection
  • oncolytic virotherapy
  • antiviral therapy
  • multiscale modeling
  • spatial modeling

Published Papers

This special issue is now open for submission.
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