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Correction published on 16 August 2021, see Viruses 2021, 13(8), 1616.
Article

Genome Sequence and Characterization of Five Bacteriophages Infecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2

Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, 52425 Jülich, Germany
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Viruses 2020, 12(10), 1065; https://doi.org/10.3390/v12101065
Received: 17 August 2020 / Revised: 18 September 2020 / Accepted: 21 September 2020 / Published: 23 September 2020
(This article belongs to the Section Bacterial Viruses)
Streptomyces are well-known antibiotic producers, also characterized by a complex morphological differentiation. Streptomyces, like all bacteria, are confronted with the constant threat of phage predation, which in turn shapes bacterial evolution. However, despite significant sequencing efforts recently, relatively few phages infecting Streptomyces have been characterized compared to other genera. Here, we present the isolation and characterization of five novel Streptomyces phages. All five phages belong to the Siphoviridae family, based on their morphology as determined by transmission electron microscopy. Genome sequencing and life style predictions suggested that four of them were temperate phages, while one had a lytic lifestyle. Moreover, one of the newly sequenced phages shows very little homology to already described phages, highlighting the still largely untapped viral diversity. Altogether, this study expands the number of characterized phages of Streptomyces and sheds light on phage evolution and phage-host dynamics in Streptomyces. View Full-Text
Keywords: phage isolation; phage genomics; Streptomyces; Siphoviridae; actinobacteriophages; actinorhodin phage isolation; phage genomics; Streptomyces; Siphoviridae; actinobacteriophages; actinorhodin
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MDPI and ACS Style

Hardy, A.; Sharma, V.; Kever, L.; Frunzke, J. Genome Sequence and Characterization of Five Bacteriophages Infecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2. Viruses 2020, 12, 1065. https://doi.org/10.3390/v12101065

AMA Style

Hardy A, Sharma V, Kever L, Frunzke J. Genome Sequence and Characterization of Five Bacteriophages Infecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2. Viruses. 2020; 12(10):1065. https://doi.org/10.3390/v12101065

Chicago/Turabian Style

Hardy, Aël, Vikas Sharma, Larissa Kever, and Julia Frunzke. 2020. "Genome Sequence and Characterization of Five Bacteriophages Infecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2" Viruses 12, no. 10: 1065. https://doi.org/10.3390/v12101065

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