Next Article in Journal
Orientation Control for Nickel-Based Single Crystal Superalloys: Grain Selection Method Assisted by Directional Columnar Grains
Previous Article in Journal
Possibilities of a Direct Synthesis of Aluminum Alloys with Elements from Deep-Sea Nodules
Previous Article in Special Issue
Tribological Characteristics of a-C:H:Si and a-C:H:SiOx Coatings Tested in Simulated Body Fluid and Protein Environment
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Materials
Volume 15
Issue 13
10.3390/ma15134466
materials-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Correlation of Cell Proliferation with Surface Properties of Polymer-like Carbon Films of Different Thicknesses Prepared by a Radio-Frequency Plasma CVD Process

by
Kazuya Kanasugi
1,*,
Hiroaki Eguchi
1,
Yasuharu Ohgoe
2,
Yoshinobu Manome
3,
Ali Alanazi
4 and
Kenji Hirakuri
1
1
Department of Electrical and Electronic Engineering, Faculty of Engineering, Tokyo Denki University, 5 Senju Asahi-cho, Adachi-ku, Tokyo 120-8551, Japan
2
Division of Electronic Engineering, Faculty of Science and Engineering, Tokyo Denki University, Ishizaka Hatoyama, Saitama 350-0394, Japan
3
Core Research Facilities, The Jikei University School of Medicine, 3-25-8, Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan
4
Applied Medical Sciences College, King Saud University, Riyadh 11451, Saudi Arabia
*
Author to whom correspondence should be addressed.
Materials 2022, 15(13), 4466; https://doi.org/10.3390/ma15134466
Submission received: 18 April 2022 / Revised: 14 June 2022 / Accepted: 21 June 2022 / Published: 24 June 2022
(This article belongs to the Special Issue Modification of Carbon-Based Coatings for Biomedical Application)
Browse Figures
Versions Notes

Abstract

In this study, correlation of cell proliferation with surface properties of the polymer-like carbon (PLC) films of different thicknesses prepared by radio-frequency plasma CVD are investigated. Four PLC samples were prepared via radio frequency plasma chemical vapor deposition on Si substrates. Each PLC film was analyzed using spectroscopic ellipsometry to determine its thickness, refractive index (n), and extinction coefficient (k); the thickness ranged from 29.0 to 356.5 nm. Based on their n–k plots, all the samples were classified as PLC-type films. The biological response of the PLC films was evaluated in vitro using a cell culture. The samples with relatively thick PLC films (>300 nm) exhibited stronger cell proliferation properties than those with thinner films. Moreover, the results of the surface analysis showed no significant differences in the surface composition of those PLC samples, as analyzed using X-ray photoelectron spectroscopy, but that as the PLC films became thicker, their surfaces became rougher on the nanoscale and their wettability improved. Overall, this study showed that careful control of the film growth of PLC films, which affects their surface properties, is essential for their use in bio-interface applications.
Keywords: cell proliferation; polymer-like carbon films; optical classification; film thickness cell proliferation; polymer-like carbon films; optical classification; film thickness

Share and Cite

MDPI and ACS Style

Kanasugi, K.; Eguchi, H.; Ohgoe, Y.; Manome, Y.; Alanazi, A.; Hirakuri, K. Correlation of Cell Proliferation with Surface Properties of Polymer-like Carbon Films of Different Thicknesses Prepared by a Radio-Frequency Plasma CVD Process. Materials 2022, 15, 4466. https://doi.org/10.3390/ma15134466

AMA Style

Kanasugi K, Eguchi H, Ohgoe Y, Manome Y, Alanazi A, Hirakuri K. Correlation of Cell Proliferation with Surface Properties of Polymer-like Carbon Films of Different Thicknesses Prepared by a Radio-Frequency Plasma CVD Process. Materials. 2022; 15(13):4466. https://doi.org/10.3390/ma15134466

Chicago/Turabian Style

Kanasugi, Kazuya, Hiroaki Eguchi, Yasuharu Ohgoe, Yoshinobu Manome, Ali Alanazi, and Kenji Hirakuri. 2022. "Correlation of Cell Proliferation with Surface Properties of Polymer-like Carbon Films of Different Thicknesses Prepared by a Radio-Frequency Plasma CVD Process" Materials 15, no. 13: 4466. https://doi.org/10.3390/ma15134466

APA Style

Kanasugi, K., Eguchi, H., Ohgoe, Y., Manome, Y., Alanazi, A., & Hirakuri, K. (2022). Correlation of Cell Proliferation with Surface Properties of Polymer-like Carbon Films of Different Thicknesses Prepared by a Radio-Frequency Plasma CVD Process. Materials, 15(13), 4466. https://doi.org/10.3390/ma15134466

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop