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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
Review

Molecular Targets and Novel Therapeutic Avenues in Soft-Tissue Sarcoma

by 1,2,* and 1
1
Cedars Cancer Centre, Department of Oncology, McGill University Health Centre, Montreal, QC, Canada
2
Segal Cancer Centre, Department of Oncology, Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2020, 27(s1), 34-40; https://doi.org/10.3747/co.27.5631
Received: 11 November 2019 / Revised: 14 December 2019 / Accepted: 5 January 2020 / Published: 1 February 2020
Soft-tissue sarcoma (sts) represents a heterogeneous group of rare tumours, and a significant number of affected patients will develop metastatic disease. Outcomes in the population with metastatic disease are generally poor, especially after progression on standard chemotherapy. The advent of personalized medicine has permitted oncologists to offer targeted treatment, thus addressing the limited treatment options and poor prognosis after progression on first-line chemotherapy. In this review, we delineate the existing data and therapeutic successes with respect to existing and emerging molecular targets in sts and options for immunotherapy in sts. Our review also summarizes emerging clinical trials that are currently recruiting patients.
Keywords: sarcoma; chemotherapy; targeted therapy; immunotherapy sarcoma; chemotherapy; targeted therapy; immunotherapy
MDPI and ACS Style

Elkrief, A.; Alcindor, T. Molecular Targets and Novel Therapeutic Avenues in Soft-Tissue Sarcoma. Curr. Oncol. 2020, 27, 34-40. https://doi.org/10.3747/co.27.5631

AMA Style

Elkrief A, Alcindor T. Molecular Targets and Novel Therapeutic Avenues in Soft-Tissue Sarcoma. Current Oncology. 2020; 27(s1):34-40. https://doi.org/10.3747/co.27.5631

Chicago/Turabian Style

Elkrief, A., and T. Alcindor. 2020. "Molecular Targets and Novel Therapeutic Avenues in Soft-Tissue Sarcoma" Current Oncology 27, no. s1: 34-40. https://doi.org/10.3747/co.27.5631

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