2016 February - 23 articles
Following up on its first workshop—the Current Oncology Scholar’s Forum and Workshop—on 12 May 2012 in China, Current Oncology initiated a 2nd conference in 2015, to communicate with Chinese and other Asian physicians and researchers, with the aim of...
Objective: We explored the role of insulin-like growth factor 1 (igf-1) in the development of lung cancer. We used immunohistochemistry to measure the expression of igf-1 and igf-1 receptor (igf-1r) in specimens of tissue and perioperative circulatio...
Background: Sperm cryopreservation remains the only clinically feasible option to preserve male fertility. The quality of counselling provided by the treating physicians and the cost of sperm cryopreservation can both influence a patient’s decision a...
Objectives: Adenoid cystic carcinoma (ACC) is often treated with surgery, with or without adjuvant radiation therapy (RT). We evaluated disease characteristics, treatments, and potentially prognostic variables in patients with ACC. Methods: Our retr...
T-Cell acute lymphoblastic leukemia (T-ALL) is a malignancy of white blood cells, characterized by an uncontrolled accumulation of T-cell progenitors. During leukemic progression, immature T cells grow abnormally and crowd into the bone marrow, preve...
Infections are a major cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), who typically have increased susceptibility because of hypogammaglobulinemia (HGG) related to their disease and its treatment. Immunoglobulin...
The annual Eastern Canadian Colorectal Cancer Consensus Conference held in Montreal, Quebec, 17–19 October 2013, marked the 10-year anniversary of this meeting that is attended by leaders in medical, radiation, and surgical oncology. The goal of the...
Background: Many prostate cancers (pcas) are indolent and, if left untreated, are unlikely to cause death or morbidity in a man’s lifetime. As a result of testing for prostate-specific antigen, more such cases are being identified, leading to concern...
As a doctor with particular experience, when you see a patient with a certain unfortunate skin color [...]
Objective: We explored the relationship between HLA-DRB1 allele polymorphisms and familial aggregation of hepatocellular carcinoma (fHCC). Methods: Polymerase chain reaction sequence-specific primers were used to determine HLA-DRB1 genotypes for 130...
Background: Previous studies suggest a combined effect of insulin-like growth factor 1 (IGF-1) and IGF binding protein 3 (IGFBP-3) gene polymorphisms, xenoestrogen, and phytoestrogen on the IGF-1 signalling pathway and serum concentrations in the IGF...
Objective: Our correlation study investigated the relationships of the expression of hepcidin and ferroportin (FPN) in tissues and serum from breast cancer (BCa) patients and the relationships of hepcidin and FPN with anemia. Methods: We used ELISA a...
Background: Effective treatment for breast cancer–related chronic lymphedema (BCRL) remains a clinical challenge. Acupuncture and moxibustion treatments have been shown to be beneficial and safe for treating BCRL. In the present randomized controlled...
Background: Although the heart is one of the body’s vital organs, with an abundant blood supply, metastasis to the heart is considered rare. In a previous study, we found that the myocardial microenvironment might contain a low molecular weight natur...
Purpose: We compared dosimetry and clinical toxicity for 3-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT), and RapidArc (Varian Medical Systems, Palo Alto, CA, U.S.A.) in locally advanced pancreatic cancer (LAPCC...
Here, we present the basic concept and theoretical framework of a scientific hypothesis called Cancer Evolution–Development (“Cancer Evo-Dev”), based on our recent studies of the molecular mechanisms by which chronic infection with the hepatitis B vi...
Introduction: Survival in uveal melanoma has remained unchanged since the early 1970s. Because outcomes are highly related to the size of the tumour, timely and accurate diagnosis can increase the chance for cure. Methods: A consensus-based guideline...
Oxaliplatin plays a major role in the treatment of colorectal cancer (CRC), but is associated with the development of neuropathies. The main objective of the present prospective study was to estimate the proportion of participants with grade 1, 2, 3,...
Synchronous cancers of different primary origin are rare. Here, we describe the case of a patient with concomitant diagnoses of rectal adenocarcinoma and splenic marginal zone lymphoma (smzl). A 57-year-old woman initially presented with abdominal pa...
In recent years, the incredible expansion of e-mail has changed the way we all practice medicine [...]
Despite advances in therapy, bone remains the most common site of prostate cancer recurrence [...]
The word “hypnosis” seems to carry somewhat different connotations today than in the past [...]
Introduction: Combretastatins, which are excellent anticancer agents, are isolated from Combretum. A sensitive ultra-performance liquid chromatography tandem mass spectrometry method was developed and validated for the pharmacokinetic study of a comb...
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