Current Oncology, Volume 23, Issue 2

Background: In 2009, the Program in Evidence-based Care (pebc) of Cancer Care Ontario published a guideline on the follow-up of cervical cancer. In 2014, the pebc undertook an update of the systematic review and clinical practice guideline for women...

Monitoring and reporting on cancer survival provides a mechanism for understanding the effectiveness of Canada’s cancer care system. Although 5-year relative survival for colorectal cancer and lung cancer has been previously reported, only recently h...

Cancer clinical trials (ccts) are essential for furthering knowledge and developing effective interventions to improve the lives of people living with cancer in Canada. Randomized controlled trials are particularly important for developing evidence-b...

Oncology is a small world in Canada, but the practice each individual undertakes is unique. [...]

Congratulations, you’ve made it! After years of studying, subspecialist training, and rounds of interviews, you have a staff position [...]

Purpose: The relative distribution of research output across cancer sites is not well described. Here, we evaluate whether the volume of published research is proportional to the public health burden of individual cancers. We also explore whether res...

Background: Cancer quality indicators have previously been described for a single tumour site or a single treatment modality, or according to distinct data sources. Our objective was to identify cancer quality indicators across all treatment modaliti...

Background: Outcomes in metastatic breast cancer (MBC) positive for HER2 (human epidermal growth factor receptor 2) are generally unfavourable. Trastuzumab has revolutionized the prognosis of HER2-positive mbc. Some HER2-positive mbc patients go into...

Breakthrough cancer pain (BTCP) represents an important element in the spectrum of cancer pain management. Because most BTCP episodes peak in intensity within a few minutes, speed of medication onset is crucial for proper control. In Canada, several...

Purpose: The aim of the present study was to assess patient satisfaction with PYNK: Breast Cancer Program for Young Women so as to determine how the program might be improved and to provide feedback to donors. Methods: All PYNK patients who had conse...

Objectives: The objectives of the present study were to estimate the overall and specific medical care costs associated with cervical cancer in the first 5 years after diagnosis in Ontario. Methods: Incident cases of invasive cervical cancer during 2...

Background: Recent studies have suggested an effect of metformin on mortality for patients with both diabetes and colorectal cancer (CRC). However, the literature is contradictory, with both positive and negative effects being identified. We set out...

Background: Hematogones (HGS) are normal B-lymphocyte precursors that increase in some hematologic diseases. Many studies indicate that HGS might be a favourable prognostic factor. We thus considered it important to determine whether HGS are also a p...

Objectives: Definitive concurrent chemoradiotherapy (CCRT) is currently a therapeutic option for locally advanced esophageal cancer. However, clinical practice differs with respect to the target volume for irradiation. The purpose of the present stud...

Background: In many hospitals, resource barriers preclude the use of preoperative multidisciplinary cancer conferences (MCCS) for consecutive patients with cancer. Collaborative cancer conferences (CCCS) are modified MCCS that might overcome such bar...

Background: More than 30 exposures in the workplace are proven carcinogens. In the present study, we aimed to estimate the burden of occupational cancer in Quebec so as to increase awareness among stakeholders and to prioritize research activities. M...

Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine tumour of the skin. Remission rates are high with chemotherapy in patients with metastasis, but without any improvement in overall survival. We present the case of a 90-year-old woman...

Clinical Scenario: During routine staging work-up for a left breast mass, a 68-year-old woman complained of dysphagia and dysphonia. During further investigations, a left-sided lesion at the foramen magnum was observed on brain imaging. Both lesions...

We read with great interest the article of Ma and colleagues titled “An exploratory comparative analysis of tyrosine kinase inhibitors or docetaxel in second-line treatment of EGFR wild-type non-small-cell lung cancer: a retrospective real-world prac...

We thank Drs. Ibrahim Elghissassi, Saber Boutayeb, Hanane Inrhaoun, Hind Mrabti, and Hassan Errihani for their comments on our paper [...]

Cancer is the most common disease-related cause of death in 15- to 29-year-olds in Canada [...]

Background: Non-small-cell lung cancer (NSCLC) is associated with very poor overall survival because 70% of patients present with locally advanced or metastatic disease at the time of diagnosis. MicroRNAS (miRNAS) are a class of short, noncoding RNA...

Background: Although APPL1 is overexpressed in many cancers, its status in gastric cancer (GC) is not known. In the present study, we used relevant pathologic and clinical data to investigate APPL1 expression in patients with GC. Methods: In 47 GC an...