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  • Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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1 June 2013

Liposomal Doxorubicin Plus Radiofrequency Ablation for Complete Necrosis of a Hepatocellular Carcinoma

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and
1
Center for Interventional Oncology, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA
2
Lerner College of Medicine, Cleveland Clinic, Cleveland, OH 44106, USA
3
Montefiore–Einstein Center for Cancer Care, Department of Surgery, Albert Einstein College of Medicine, Bronx, NY 10467, USA
4
National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Curr. Oncol.2013, 20(3), 274-277;https://doi.org/10.3747/co.20.1266
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Abstract

Radiofrequency ablation (RFA) is a standard treatment for small, unresectable hepatocellular carcinomas (HCCS). However, RFA for larger tumours is less successful, and intravenous lyso-thermosensitive liposomal doxorubicin during RFA is one technique postulated to potentially address that limitation. This drug-plus-device combination therapy was used to completely treat a HCC in a patient who underwent liver transplantation 79 days later.

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