Cardiac and Cognitive Effects of Androgen Deprivation Therapy: Are They Real?

Shabbir M. H. Alibhai; H. Z. Mohamedali

doi:10.3747/co.v17i0.698

Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..

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1 September 2010

Cardiac and Cognitive Effects of Androgen Deprivation Therapy: Are They Real?

and

Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, ON M5G 2C4, Canada

Geriatric Program, Toronto Rehabilitation Institute, Toronto, ON, Canada

Departments of Medicine and of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada

Author to whom correspondence should be addressed.

Curr. Oncol.2010, 17(s2), 55-64;https://doi.org/10.3747/co.v17i0.698

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Abstract

With androgen deprivation therapy being used ever earlier and longer in the course of prostate cancer, concerns have emerged about a variety of adverse effects, including cardiovascular disease and cognitive dysfunction. Conflicting data in both areas have led to controversy and confusion. Here, we review published data in an attempt to clarify those issues.

Keywords:

prostatic neoplasms; androgen deprivation therapy; cardiac disease; cognition; adverse effects

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