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Article

A New Anthracene Derivative from Marine Streptomyces sp. W007 Exhibiting Highly and Selectively Cytotoxic Activities

1
Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China
2
Graduate University of Chinese Academy of Sciences, Beijing 100049, China
3
Department of Organic and Biomolecular Chemistry, University of Göttingen, Göttingen D-37077, Germany
4
Yantai Institute of China Agricultural University, China Agricultural University, Yantai 264670, China
5
Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
*
Author to whom correspondence should be addressed.
Mar. Drugs 2011, 9(9), 1502-1509; https://doi.org/10.3390/md9091502
Received: 12 July 2011 / Revised: 17 August 2011 / Accepted: 19 August 2011 / Published: 9 September 2011
A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[α]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR (1H–1H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[α]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549. View Full-Text
Keywords: Streptomyces; anthracene; structure establishment; cytotoxicity Streptomyces; anthracene; structure establishment; cytotoxicity
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MDPI and ACS Style

Zhang, H.; Wang, H.; Cui, H.; Li, Z.; Xie, Z.; Pu, Y.; Li, F.; Qin, S. A New Anthracene Derivative from Marine Streptomyces sp. W007 Exhibiting Highly and Selectively Cytotoxic Activities. Mar. Drugs 2011, 9, 1502-1509. https://doi.org/10.3390/md9091502

AMA Style

Zhang H, Wang H, Cui H, Li Z, Xie Z, Pu Y, Li F, Qin S. A New Anthracene Derivative from Marine Streptomyces sp. W007 Exhibiting Highly and Selectively Cytotoxic Activities. Marine Drugs. 2011; 9(9):1502-1509. https://doi.org/10.3390/md9091502

Chicago/Turabian Style

Zhang, Hongyu, Hongpeng Wang, Hongli Cui, Zonggang Li, Zeping Xie, Yang Pu, Fuchao Li, and Song Qin. 2011. "A New Anthracene Derivative from Marine Streptomyces sp. W007 Exhibiting Highly and Selectively Cytotoxic Activities" Marine Drugs 9, no. 9: 1502-1509. https://doi.org/10.3390/md9091502

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