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Mar. Drugs 2018, 16(4), 118;

Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods

Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Qld, Australia
Authors to whom correspondence should be addressed.
Received: 7 February 2018 / Revised: 21 March 2018 / Accepted: 29 March 2018 / Published: 5 April 2018
(This article belongs to the Collection Bioactive Compounds from Marine Invertebrates)
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A diverse range of predatory marine gastropods produce toxins, yet most of these molecules remain uncharacterized. Conus species have received the most attention from researchers, leading to several conopeptides reaching clinical trials. This review aims to summarize what is known about bioactive compounds isolated from species of neglected marine gastropods, especially in the Turridae, Terebridae, Babyloniidae, Muricidae, Buccinidae, Colubrariidae, Nassariidae, Cassidae, and Ranellidae families. Multiple species have been reported to contain bioactive compounds with potential toxic activity, but most of these compounds have not been characterized or even clearly identified. The bioactive properties and potential applications of echotoxins and related porins from the Ranellidae family are discussed in more detail. Finally, the review concludes with a call for research on understudied species. View Full-Text
Keywords: toxins; marine gastropods; salivary glands; peptides; Ranellidae; echotoxins toxins; marine gastropods; salivary glands; peptides; Ranellidae; echotoxins

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Turner, A.H.; Craik, D.J.; Kaas, Q.; Schroeder, C.I. Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods. Mar. Drugs 2018, 16, 118.

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