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5 December 2013

3 Pages

Valproic Acid-Induced Pancreatitis in a 15-Year-Old Boy With Juvenile Myoclonic Epilepsy

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Department of Pediatrics, University of Tartu, 2Children's Clinic, Tartu University Hospital, Estonia
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Abstract

Drug-induced acute pancreatitis is a rare condition in childhood, and information about the incidence of valproic acid-induced acute pancreatitis in the pediatric population is scarce. In this clinical case, we report a first documented pediatric case of valproic acid-induced pancreatitis in Estonia. A 15-year-old boy with juvenile myoclonic epilepsy developed acute pancreatitis after 2-month therapy with valproic acid. The symptoms of pancreatitis subsided within 1 week after the discontinuation of treatment with valproic acid. Acute pancreatitis should be suspected in any pedi- atric patient with gastrointestinal symptoms during valproate treatment

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