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Current Issues in Molecular Biology, Volume 44, Issue 9

September 2022 - 39 articles

Cover Story: The chain of correlation between the processes responsible for embryo implantation and the subsequent physiological course of pregnancy is complicated. On the one hand, the induction of inflammation during implantation is necessary. On the other hand, an abnormal response from any side might result in a pregnancy failure or a pathological course of pregnancy. In this review, we summarize recognized mechanisms and the significance of inflammatory processes for embryo implantation and pregnancy establishment. Additionally, we present disorders involving an excessive inflammatory response and their influence on events occurring during embryo implantation. View this paper
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Articles (39)

  • Article
  • Open Access
3 Citations
2,810 Views
19 Pages

12 September 2022

Cinnamomum burmannii is a cinnamomum plant rich in natural D-borneol. Natural D-borneol is a bicycle monoterpenoid compound widely used in the food, pharmaceutical, and cosmetic industries. Therefore, analyzing the biosynthesis mechanism of natural D...

  • Review
  • Open Access
14 Citations
4,079 Views
16 Pages

Metabolomics as a Prospective Tool for Soybean (Glycine max) Crop Improvement

  • Efficient Ncube,
  • Keletso Mohale and
  • Noluyolo Nogemane

12 September 2022

Global demand for soybean and its products has stimulated research into the production of novel genotypes with higher yields, greater drought and disease tolerance, and shorter growth times. Genetic research may be the most effective way to continue...

  • Article
  • Open Access
9 Citations
3,893 Views
14 Pages

12 September 2022

Under specific cultivation conditions, the sepal color of Hydrangea macrophylla (H. macrophylla) changes from red to blue due to the complexation of aluminum ions (Al3+), delphinidin 3-glucoside, and copigments. However, this phenomenon cannot occur...

  • Review
  • Open Access
21 Citations
3,981 Views
15 Pages

Polyphenols and Small Phenolic Acids as Cellular Metabolic Regulators

  • Mark Obrenovich,
  • Yi Li,
  • Moncef Tayahi and
  • V. Prakash Reddy

9 September 2022

Polyphenols and representative small phenolic acids and molecules derived from larger constituents are dietary antioxidants from fruits, vegetables and largely other plant-based sources that have ability to scavenge free radicals. What is often negle...

  • Article
  • Open Access
2 Citations
2,656 Views
10 Pages

Prognostic Impact of Low-Level p53 Expression on Brain Astrocytomas Immunopositive for Epidermal Growth Factor Receptor

  • Hung-Pei Tsai,
  • Chien-Ju Lin,
  • Chieh-Hsin Wu,
  • Yi-Ting Chen,
  • Ying-Yi Lu,
  • Aij-Lie Kwan and
  • Ann-Shung Lieu

9 September 2022

Although the expression of p53 and epidermal growth factor receptor (EGFR) is associated with therapeutic resistance and patient outcomes in many malignancies, the relationship in astrocytomas is unclear. This study aims to correlate p53 and EGFR exp...

  • Article
  • Open Access
8 Citations
3,717 Views
10 Pages

Detection of Mutations in pncA in Mycobacterium tuberculosis Clinical Isolates from Nepal in Association with Pyrazinamide Resistance

  • Dipti Shrestha,
  • Bhagwan Maharjan,
  • Jeewan Thapa,
  • Mwangala Lonah Akapelwa,
  • Precious Bwalya,
  • Joseph Yamweka Chizimu,
  • Chie Nakajima and
  • Yasuhiko Suzuki

8 September 2022

Without the proper information on pyrazinamide (PZA) susceptibility of Mycobacterium tuberculosis (MTB), PZA is inappropriately recommended for the treatment of both susceptible and multidrug-resistant tuberculosis (MDR-TB) in Nepal. This study aimed...

  • Article
  • Open Access
2 Citations
3,203 Views
14 Pages

7 September 2022

Melanoma is a lethal form of skin cancer. Immunotherapeutic agents such as anti-PD-1 (pembrolizumab and nivolumab) and anti-CTLA-4 (ipilimumab) have revolutionized melanoma treatment; however, drug resistance is rapidly acquired. Several studies have...

  • Article
  • Open Access
9 Citations
3,162 Views
18 Pages

7 September 2022

This study aimed to explore the possible relationship between the expression of Micro RNA-214 (miR-214) and the pathogenesis and recovery in mice with post-traumatic osteoarthritis (PTOA). In this study, 40 male C57BL/6 mice were randomly divided int...

  • Article
  • Open Access
19 Citations
3,633 Views
13 Pages

7 September 2022

The escalating prevalence of antibiotic-resistant bacteria has led to a serious global public health problem; therefore, there is an urgent need for the development of structurally innovative antibacterial agents. In our study, a series of biphenyl a...

  • Article
  • Open Access
12 Citations
3,023 Views
17 Pages

Phosphorus Regulates the Level of Signaling Molecules in Rice to Reduce Cadmium Toxicity

  • Qiaoyu Chen,
  • Yanyan Hu,
  • Lijun Yang,
  • Benguo Zhu and
  • Feng Luo

7 September 2022

Phosphorus treatment can reduce Cd accumulation and Cd toxicity in rice, but alterations in the internal regulatory network of rice during this process have rarely been reported. We have removed the effect of cadmium phosphate precipitation from the...

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Curr. Issues Mol. Biol. - ISSN 1467-3045