An Introduction to Peptide Nucleic Acid

Peter E. Nielsen; Michael Egholm

doi:10.21775/cimb.001.089

You are currently viewing a new version of our website. To view the old version click .

Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.

Review

31 July 1999

An Introduction to Peptide Nucleic Acid

and

The Panum Institute, DK-2200 Copenhagen N, Denmark

PE Biosystems, 500 Old Connecticut Path, Framingham, MA 01701, USA

Curr. Issues Mol. Biol.1999, 1(2), 89-104;https://doi.org/10.21775/cimb.001.089

Version Notes

Order Reprints

Abstract

Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.

Article Metrics

Citations

Article Access Statistics

Journal Statistics

Multiple requests from the same IP address are counted as one view.

Endonuclease-Mediated Long PCR and Its Application to Restriction Mapping

Purification of Nucleic Acids by Hybridization to Affinity Tagged PNA Probes