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International Journal of Molecular Sciences, Volume 8, Issue 11

2007 November - 8 articles

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Articles (8)

  • Article
  • Open Access
10 Citations
9,604 Views
19 Pages

27 November 2007

Ginkgolide B, the major active component of Ginkgo biloba extracts, can bothstimulate and inhibit apoptotic signaling. Here, we demonstrate that ginkgolide B caninduce the production of reactive oxygen species in MCF-7 breast cancer cells, leading to...

  • Article
  • Open Access
18 Citations
10,488 Views
12 Pages

Inhibition of Acetylcholinesterase in Different Structures of the Rat Brain Following Soman Intoxication Pretreated with Huperzine A

  • Jiri Bajgar,
  • Petr Hajek,
  • Jana Karasova,
  • Dasa Slizova,
  • Otakar Krs,
  • Kamil Kuca,
  • Daniel Jun,
  • Josef Fusek and
  • Lukas Capek

26 November 2007

Acetylcholinesterase (AChE) activities in different brain parts were determinedquantitatively in rats treated with huperzine A, soman, and huperzine A followed bysoman, using histochemical and biochemical methods. Following soman intoxication (1.2x L...

  • Article
  • Open Access
20 Citations
10,098 Views
33 Pages

22 November 2007

The paper presents a unitary approach of the use of a Molecular DescriptorsFamily in structure-property/activity relationships, particularly in modelling thechromatographic retention times of polychlorinated biphenyls. Starting from molecularstructur...

  • Article
  • Open Access
2 Citations
7,737 Views
7 Pages

22 November 2007

We report the measured total charge-transfer (electron-capture) cross sectionsfor the ground state O2+ (X2πg) ions with H2 and O2 molecular gases in the collisionenergy range between 0.50 and 2 keV. The time-of-flight technique has been used tomeasur...

  • Article
  • Open Access
49 Citations
11,996 Views
14 Pages

21 November 2007

A set of 13 fatty acids was transformed into their phenacyl esters by reaction withphenacyl bromide in acetonitrile using 18-crown-6 as phase-transfer catalyst. Conditions forthe RP-18 HPL chromatographic separation of most of the esters has been wor...

  • Article
  • Open Access
12 Citations
9,910 Views
16 Pages

1 November 2007

The objectives of this study were to isolate various isoflavone fractions andextracts from soybean cake by preparative column chromatography and compare themwith isoflavone standards with regards to inhibition of HepG2 cancer cell proliferation.Four...

  • Article
  • Open Access
10 Citations
15,236 Views
12 Pages

31 October 2007

ATP is involved in numerous biochemical reactions in living cells interacting withdifferent proteins. Molecular docking simulations provide considerable insight into theproblem of molecular recognition of this substrate. To improve the selection of c...

  • Article
  • Open Access
9 Citations
21,863 Views
19 Pages

29 October 2007

Geometric parameters and FT-IR spectrum of 6-bromo-8-thia-1,4-epoxybicyclo[4.3.0]non-2-ene were computed by the HF, B3LYP, B3PW91 andmPW1PW91 methods in conjunction with the 6-31G(d,p) basis set. The calculated IRspectra are in a good agreement with...

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Int. J. Mol. Sci. - ISSN 1422-0067