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International Journal of Molecular Sciences, Volume 23, Issue 24

December-2 2022 - 782 articles

Cover Story: Solid-state nanoparticles are continuing to attract interest for their great medical potential thanks to their countless properties and possible applications. This work aims to give a comprehensive overview of the latest developments in the use of artificial liposomes and naturally derived extracellular vesicles for the coating of solid-state nanoparticles for cancer treatment, starting from in vitro works until the up-to-date advances and current limitations of these nanopharmaceutics in clinical applications, passing through in vivo and 3D cultures studies. View this paper
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Articles (782)

  • Article
  • Open Access
9 Citations
3,441 Views
14 Pages

Highly Efficient Removal of Uranium from an Aqueous Solution by a Novel Phosphonic Acid-Functionalized Magnetic Microsphere Adsorbent

  • Jizhou Zhao,
  • Peng Lu,
  • Tengteng He,
  • Jing Huang,
  • Shiao Zhang,
  • Yan Liu,
  • Yun Wang,
  • Cheng Meng and
  • Dingzhong Yuan

19 December 2022

The development of adsorption materials which can efficiently isolate and enrich uranium is of great scientific significance to sustainable development and environmental protection. In this work, a novel phosphonic acid-functionalized magnetic micros...

  • Review
  • Open Access
54 Citations
16,135 Views
25 Pages

Fatty Liver Disease-Alcoholic and Non-Alcoholic: Similar but Different

  • Stephen D. H. Malnick,
  • Pavel Alin,
  • Marina Somin and
  • Manuela G. Neuman

19 December 2022

In alcohol-induced liver disease (ALD) and in non-alcoholic fatty liver disease (NAFLD), there are abnormal accumulations of fat in the liver. This phenomenon may be related to excessive alcohol consumption, as well as the combination of alcohol cons...

  • Review
  • Open Access
18 Citations
8,386 Views
24 Pages

Cardiac Sarcomere Signaling in Health and Disease

  • Ashley A. Martin,
  • Brian R. Thompson,
  • Dongwoo Hahn,
  • Addeli Bez Batti Angulski,
  • Nora Hosny,
  • Houda Cohen and
  • Joseph M. Metzger

19 December 2022

The cardiac sarcomere is a triumph of biological evolution wherein myriad contractile and regulatory proteins assemble into a quasi-crystalline lattice to serve as the central point upon which cardiac muscle contraction occurs. This review focuses on...

  • Review
  • Open Access
15 Citations
4,178 Views
13 Pages

19 December 2022

Both fasting and non-fasting hypertriglyceridemia have emerged as residual risk factors for atherosclerotic disease. However, it is unclear whether hypertriglyceridemia increases the risks of the progression of carotid artery stenosis. Statins are we...

  • Article
  • Open Access
6 Citations
2,900 Views
14 Pages

Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants

  • Nesrine Baatallah,
  • Ahmad Elbahnsi,
  • Benoit Chevalier,
  • Solène Castanier,
  • Jean-Paul Mornon,
  • Iwona Pranke,
  • Aleksander Edelman,
  • Isabelle Sermet-Gaudelus,
  • Isabelle Callebaut and
  • Alexandre Hinzpeter

19 December 2022

ABC transporters are large membrane proteins sharing a complex architecture, which comprises two nucleotide-binding domains (NBDs) and two membrane-spanning domains (MSDs). These domains are susceptible to mutations affecting their folding and assemb...

  • Article
  • Open Access
4 Citations
2,978 Views
11 Pages

Dysregulated Expression of Transposable Elements in TDP-43M337V Human Motor Neurons That Recapitulate Amyotrophic Lateral Sclerosis In Vitro

  • Braulio Valdebenito-Maturana,
  • Matias Ignacio Rojas-Tapia,
  • Mónica Carrasco and
  • Juan Carlos Tapia

19 December 2022

Amyotrophic lateral sclerosis (ALS) is a disease that progressively annihilates spinal cord motor neurons, causing severe motor decline and death. The disease is divided into familial and sporadic ALS. Mutations in the TAR DNA binding protein 43 (TDP...

  • Article
  • Open Access
6 Citations
5,968 Views
17 Pages

CRISPR/Cas9-Mediated Gene Editing in Salmonids Cells and Efficient Establishment of Edited Clonal Cell Lines

  • Trygve A. H. Strømsnes,
  • Sebastian E. Schmidke,
  • Mitra Azad,
  • Øyvind Singstad,
  • Idun M. Grønsberg,
  • Roy A. Dalmo and
  • Arinze S. Okoli

19 December 2022

Finfish production has seen over three-fold increase in the past 30 years (1990–2020), and Atlantic salmon (A. salmon; salmo salar) accounted for approximately 32.6% of the total marine and coastal aquaculture of all finfish species in the year...

  • Article
  • Open Access
8 Citations
2,772 Views
19 Pages

19 December 2022

Tetranychus urticae Koch (T. urticae) is one of the most tremendous herbivores due to its polyphagous characteristics, and is resistant to most acaricides. In this study, enzyme-linked immunosorbent assay (ELISA), transcriptome sequencing (RNA-seq) a...

  • Review
  • Open Access
18 Citations
15,073 Views
21 Pages

Mitochondrial Aging and Senolytic Natural Products with Protective Potential

  • Andrea Deledda,
  • Emanuele Giordano,
  • Fernanda Velluzzi,
  • Giovanna Flore,
  • Sara Franceschelli,
  • Lorenza Speranza and
  • Patrizio Ripari

19 December 2022

Living organisms do not disregard the laws of thermodynamics and must therefore consume energy for their survival. In this way, cellular energy exchanges, which aim above all at the production of ATP, a fundamental molecule used by the cell for its m...

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Int. J. Mol. Sci. - ISSN 1422-0067