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Open AccessArticle

Fabrication and Characterization of Polyetherimide Electrospun Scaffolds Modified with Graphene Nano-Platelets and Hydroxyapatite Nano-Particles

1
Department of Mechanical Engineering and Aeronautics, University of Patras, Patras University Campus, GR-26504 Patras, Greece
2
Foundation of Research and Technology, Institute of Chemical Engineering Sciences (FORTH/ICE-HT), Stadiou Str., GR-26504 Patras, Greece
3
Department of Mechanical Engineering, School of Engineering, University of Peloponnese, M. Alexandrou 1, Koukouli, GR-26334 Patras, Greece
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(2), 583; https://doi.org/10.3390/ijms21020583
Received: 13 December 2019 / Revised: 10 January 2020 / Accepted: 13 January 2020 / Published: 16 January 2020
(This article belongs to the Special Issue Polymeric Scaffolds: Design, Processing, and Biomedical Application)
Solution electrospinning process (SEP) is a versatile technique for generating non-woven fibrous materials intended to a wide range of applications. One of them is the production of fibrous and porous scaffolds aiming to mimic bone tissue, as artificial extracellular matrices (ECM). In the present work, pure and nano-modified electrospun polyetherimide (PEI) scaffolds have been successfully fabricated. The nano-modified ones include (a) graphene nano-platelets (GNPs), (b) hydroxyapatite (HAP), and (c) mixture of both. After fabrication, the morphological characteristics of these scaffolds were revealed by using scanning electron (SEM) and transmission electron (TEM) microscopies, while porosity and mean fiber diameter were also calculated. In parallel, contact angle experiments were conducted so that the hydrophilicity level of these materials to be determined. Finally, the mechanical performance of the fabricated scaffolds was investigated by conducting uniaxial tensile tests. Ιn future work, the fabricated scaffolds will be further utilized for investigation as potential candidate materials for cell culture with perspective in orthopedic applications. View Full-Text
Keywords: solution electrospinning; scaffolds; bone tissue engineering; polyetherimide; GNPs; hydroxyapatite; SEM; TEM; contact angle; mechanical properties solution electrospinning; scaffolds; bone tissue engineering; polyetherimide; GNPs; hydroxyapatite; SEM; TEM; contact angle; mechanical properties
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MDPI and ACS Style

Kostopoulos, V.; Kotrotsos, A.; Fouriki, K.; Kalarakis, A.; Portan, D. Fabrication and Characterization of Polyetherimide Electrospun Scaffolds Modified with Graphene Nano-Platelets and Hydroxyapatite Nano-Particles. Int. J. Mol. Sci. 2020, 21, 583.

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