Renoprotective Effects of Hypoxylonol C and F Isolated from Hypoxylon truncatum against Cisplatin-Induced Cytotoxicity in LLC-PK1 Cells
Abstract
:1. Introduction
2. Results and Discussion
2.1. Protective Effect of H. truncatum Extract against Cisplatin-Induced LLC-PK1 Cell Death
2.2. Effects of Hypoxylonol F (2) on Cisplatin-Induced Apoptosis in LLC-PK1 Cells
3. Materials and Methods
3.1. General Experimental Procedures
3.2. Mushroom Material
3.3. Extraction and Isolation
3.4. Cell Culture and MTT Cell Viability Assay
3.5. Image-Based Cytometric Assay
3.6. Western Blotting Analysis
3.7. Statistical Analysis
4. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Hwang, B.S.; Lee, D.; Choi, P.; Kim, K.S.; Choi, S.-J.; Song, B.G.; Kim, T.; Song, J.H.; Kang, K.S.; Ham, J. Renoprotective Effects of Hypoxylonol C and F Isolated from Hypoxylon truncatum against Cisplatin-Induced Cytotoxicity in LLC-PK1 Cells. Int. J. Mol. Sci. 2018, 19, 948. https://doi.org/10.3390/ijms19040948
Hwang BS, Lee D, Choi P, Kim KS, Choi S-J, Song BG, Kim T, Song JH, Kang KS, Ham J. Renoprotective Effects of Hypoxylonol C and F Isolated from Hypoxylon truncatum against Cisplatin-Induced Cytotoxicity in LLC-PK1 Cells. International Journal of Molecular Sciences. 2018; 19(4):948. https://doi.org/10.3390/ijms19040948
Chicago/Turabian StyleHwang, Buyng Su, Dahae Lee, Pilju Choi, Kyu Sun Kim, Seon-Jun Choi, Bong Geun Song, Taejung Kim, Ji Hoon Song, Ki Sung Kang, and Jungyeob Ham. 2018. "Renoprotective Effects of Hypoxylonol C and F Isolated from Hypoxylon truncatum against Cisplatin-Induced Cytotoxicity in LLC-PK1 Cells" International Journal of Molecular Sciences 19, no. 4: 948. https://doi.org/10.3390/ijms19040948