Next Article in Journal
New Triterpenoids with Cytotoxic Activity from Actinidia Valvata
Next Article in Special Issue
Genomic Polymorphism of Human Papillomavirus Type 52 in Women from Northeast China
Previous Article in Journal
Involvement of Salicylic Acid on Antioxidant and Anticancer Properties, Anthocyanin Production and Chalcone Synthase Activity in Ginger (Zingiber officinale Roscoe) Varieties
Previous Article in Special Issue
Role of Btg2 in the Progression of a PDGF-Induced Oligodendroglioma Model
Review

The Role of Vascular Endothelial Growth Factor A Polymorphisms in Breast Cancer

Division of Head-Neck and Breast Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2012, 13(11), 14845-14864; https://doi.org/10.3390/ijms131114845
Received: 18 September 2012 / Revised: 16 October 2012 / Accepted: 1 November 2012 / Published: 13 November 2012
(This article belongs to the Special Issue Advances in Molecular Oncology (special issue))
Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator of angiogenesis, is highly expressed in cancer tissue and correlates with its more aggressive features. Polymorphisms of VEGFA alter the levels of expression and subsequently influence the susceptibility and aggressiveness of breast cancer. Assessment of VEGFA polymorphisms may be used for the identification of patients suitable for anti-VEGFA therapy. View Full-Text
Keywords: angiogenesis; breast cancer; polymorphism; vascular endothelial growth factor angiogenesis; breast cancer; polymorphism; vascular endothelial growth factor
Show Figures

MDPI and ACS Style

Sa-nguanraksa, D.; O-charoenrat, P. The Role of Vascular Endothelial Growth Factor A Polymorphisms in Breast Cancer. Int. J. Mol. Sci. 2012, 13, 14845-14864. https://doi.org/10.3390/ijms131114845

AMA Style

Sa-nguanraksa D, O-charoenrat P. The Role of Vascular Endothelial Growth Factor A Polymorphisms in Breast Cancer. International Journal of Molecular Sciences. 2012; 13(11):14845-14864. https://doi.org/10.3390/ijms131114845

Chicago/Turabian Style

Sa-nguanraksa, Doonyapat, and Pornchai O-charoenrat. 2012. "The Role of Vascular Endothelial Growth Factor A Polymorphisms in Breast Cancer" International Journal of Molecular Sciences 13, no. 11: 14845-14864. https://doi.org/10.3390/ijms131114845

Find Other Styles

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop