Next Article in Journal / Special Issue
The Complexities of Epidemiology and Prevention of Gastrointestinal Cancers
Previous Article in Journal
Microsatellite Mutation Rate during Allohexaploidization of Newly Resynthesized Wheat
Previous Article in Special Issue
Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-Beta or Carboxyl Esterase on the Growth of LNCaP Prostate Cancer Cells
Article Menu

Export Article

Open AccessReview
Int. J. Mol. Sci. 2012, 13(10), 12544-12555;

MicroRNAs as Diagnostic Biomarkers in Gastric Cancer

Institute of Clinical Research of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Road, Hangzhou 310016, China
Author to whom correspondence should be addressed.
Received: 24 July 2012 / Revised: 31 August 2012 / Accepted: 5 September 2012 / Published: 1 October 2012
(This article belongs to the Special Issue Advances in Molecular Oncology (special issue))
Full-Text   |   PDF [183 KB, uploaded 19 June 2014]


Considering the high mortality rates and the unfavorable prognosis of gastric cancer (GC) as well as the lack of a clinical predictive marker, which is sufficiently sensitive to GC, it is of great significance to investigate new sensitive and specific markers for GC diagnosis. MicroRNAs (miRNAs) could be a practical form of potential biomarkers in the diagnosis of human disease, and they are confirmed to be closely associated with GC. In this review, we discuss the recent research results that indicate the feasibility and clinical applications of miRNAs in GC. Although several challenges remain to be addressed, miRNAs have the potential to be applied in the diagnosis of GC. View Full-Text
Keywords: microRNAs; gastric cancer; biomarkers; diagnosis microRNAs; gastric cancer; biomarkers; diagnosis
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Yin, Y.; Li, J.; Chen, S.; Zhou, T.; Si, J. MicroRNAs as Diagnostic Biomarkers in Gastric Cancer. Int. J. Mol. Sci. 2012, 13, 12544-12555.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top