Next Article in Journal
Compensatory Growth Induced in Zebrafish Larvae after Pre-Exposure to a Microcystis aeruginosa Natural Bloom Extract Containing Microcystins
Next Article in Special Issue
On the Reconstruction of Three-dimensional Protein Structures from Contact Maps
Previous Article in Journal
An Overview of Conventional and Emerging Analytical Methods for the Determination of Mycotoxins
Previous Article in Special Issue
Hierarchical Clustering of Large Databases and Classification of Antibiotics at High Noise Levels
Open AccessArticle

Function Annotation of an SBP-box Gene in Arabidopsis Based on Analysis of Co-expression Networks and Promoters

College of Bioengineering, Chongqing University, Chongqing 400030, P.R. China
Beijing Research Center of Agro-Biotechnology, Beijing 100089, P.R.China
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2009, 10(1), 116-132;
Received: 21 October 2008 / Revised: 15 December 2008 / Accepted: 18 December 2008 / Published: 2 January 2009
(This article belongs to the Special Issue Algorithms and Molecular Sciences)
The SQUAMOSA PROMOTER BINDING PROTEIN–LIKE (SPL) gene family is an SBP-box transcription family in Arabidopsis. While several physiological responses to SPL genes have been reported, their biological role remains elusive. Here, we use a combined analysis of expression correlation, the interactome, and promoter content to infer the biological role of the SPL genes in Arabidopsis thaliana. Analysis of the SPL-correlated gene network reveals multiple functions for SPL genes. Network analysis shows that SPL genes function by controlling other transcription factor families and have relatives with membrane protein transport activity. The interactome analysis of the correlation genes suggests that SPL genes also take part in metabolism of glucose, inorganic salts, and ATP production. Furthermore, the promoters of the correlated genes contain a core binding cis-element (GTAC). All of these analyses suggest that SPL genes have varied functions in Arabidopsis. View Full-Text
Keywords: Arabidopsis; SPL; co-expression; network; promoter Arabidopsis; SPL; co-expression; network; promoter
Show Figures

Graphical abstract

MDPI and ACS Style

Wang, Y.; Hu, Z.; Yang, Y.; Chen, X.; Chen, G. Function Annotation of an SBP-box Gene in Arabidopsis Based on Analysis of Co-expression Networks and Promoters. Int. J. Mol. Sci. 2009, 10, 116-132.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

Only visits after 24 November 2015 are recorded.
Search more from Scilit
Back to TopTop