You are currently viewing a new version of our website. To view the old version click .

Molecules, Volume 27, Issue 12

June-2 2022 - 316 articles

Cover Story: Advanced carbon microelectrodes based on carbon nanotubes (CNTs) are being developed for the in vivo detection of neurotransmitters such as dopamine (DA). We use molecular dynamics simulations to investigate the adsorbed structures and surface diffusion dynamics of DA and related species on CNTs of varying curvature and helicity and in the groove between two aligned CNTs. We find that diffusion depends upon curvature and correlates with the vertical placement of the adsorbate’s moieties, its tilt angle, its orientation along the CNT axis, and the number of waters in its first hydration shell, all of which will influence its effective hydrodynamic radius. In addition, DA diffuses into and remains in the groove between the pair of aligned CNTs, enhancing diffusivity along the CNT axis. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (316)

  • Article
  • Open Access
12 Citations
3,327 Views
16 Pages

Quantification of Salicylates and Flavonoids in Poplar Bark and Leaves Based on IR, NIR, and Raman Spectra

  • Sylwester Mazurek,
  • Maciej Włodarczyk,
  • Sonia Pielorz,
  • Piotr Okińczyc,
  • Piotr M. Kuś,
  • Gabriela Długosz,
  • Diana Vidal-Yañez and
  • Roman Szostak

20 June 2022

Poplar bark and leaves can be an attractive source of salicylates and other biologically active compounds used in medicine. However, the biochemical variability of poplar material requires a standardization prior to processing. The official analytica...

  • Communication
  • Open Access
15 Citations
3,603 Views
11 Pages

Exosomal MicroRNA as Biomarkers for Diagnosing or Monitoring the Progression of Ovarian Clear Cell Carcinoma: A Pilot Study

  • Kayo Horie,
  • Naoki Nanashima,
  • Yoshihito Yokoyama,
  • Haruhiko Yoshioka and
  • Jun Watanabe

20 June 2022

Ovarian cancer is the most common cause of gynecological malignancy-related mortality since early-stage disease is difficult to diagnose. Advanced clear cell carcinoma of the ovary (CCCO) has dismal prognosis, and its incidence has been increasing in...

  • Article
  • Open Access
5 Citations
2,642 Views
10 Pages

Wooden-Tip Electrospray Mass Spectrometry Characterization of Human Hemoglobin in Whole Blood Sample for Thalassemia Screening: A Pilot Study

  • Tingting Huang,
  • Ting Huang,
  • Yongyi Zou,
  • Kang Xie,
  • Yinqin Shen,
  • Wen Zhang,
  • Shuhui Huang,
  • Yanqiu Liu and
  • Bicheng Yang

20 June 2022

Traditional analytical methods for thalassemia screening are needed to process complicated and time-consuming sample pretreatment. In recent decades, ambient mass spectrometry (MS) approaches have been proven to be an effective analytical strategy fo...

  • Article
  • Open Access
15 Citations
8,441 Views
12 Pages

Dielectric Properties Investigation of Metal–Insulator–Metal (MIM) Capacitors

  • Li Xiong,
  • Jin Hu,
  • Zhao Yang,
  • Xianglin Li,
  • Hang Zhang and
  • Guanhua Zhang

20 June 2022

This study presents the construction and dielectric properties investigation of atomic-layer-deposition Al2O3/TiO2/HfO2 dielectric-film-based metal–insulator–metal (MIM) capacitors. The influence of the dielectric layer material and thick...

  • Review
  • Open Access
22 Citations
5,233 Views
37 Pages

20 June 2022

Large amplitude motions (LAMs) form a fundamental phenomenon that demands the development of specific theoretical and Hamiltonian models. In recent years, along with the strong progress in instrumental techniques on high-resolution microwave spectros...

  • Article
  • Open Access
6 Citations
5,165 Views
12 Pages

20 June 2022

Double-filtration plasmapheresis (DFPP) is a blood cleaning technique that enables the removal of unwanted substances from the blood. In our case study, we performed near-infrared (NIR) spectroscopy measurements on the human hand tissue before and af...

  • Article
  • Open Access
7 Citations
4,684 Views
22 Pages

Screening of Specific and Common Pathways in Breast Cancer Cell Lines MCF-7 and MDA-MB-231 Treated with Chlorophyllides Composites

  • Keng-Shiang Huang,
  • Yi-Ting Wang,
  • Omkar Byadgi,
  • Ting-Yu Huang,
  • Mi-Hsueh Tai,
  • Jei-Fu Shaw and
  • Chih-Hui Yang

20 June 2022

Our previous findings have shown that the chlorophyllides composites have anticancer activities to breast cancer cell lines (MCF-7 and MDA-MB-231). In the present study, microarray gene expression profiling was utilized to investigate the chlorophyll...

  • Article
  • Open Access
9 Citations
3,794 Views
17 Pages

Design of Novel Enantiopure Dispirooxindolopyrrolidine-Piperidones as Promising Candidates toward COVID-19: Asymmetric Synthesis, Crystal Structure and In Silico Studies

  • Amani Toumi,
  • Sarra Boudriga,
  • Yasmine M. Mandour,
  • Ahmed A. Mekki,
  • Michael Knorr,
  • Carsten Strohmann,
  • Jan-Lukas Kirchhoff and
  • Mansour Sobeh

20 June 2022

Despite the effectiveness of COVID-19 vaccines, there is still an urgent need for discovering new anti-viral drugs to address the awful spread and transmission of the rapidly modifiable virus. In this study, the ability of a small library of enantiom...

  • Article
  • Open Access
9 Citations
3,071 Views
14 Pages

Benzamides Substituted with Quinoline-Linked 1,2,4-Oxadiazole: Synthesis, Biological Activity and Toxicity to Zebrafish Embryo

  • Bin-Long Sun,
  • Ying-Ying Wang,
  • Sen Yang,
  • Min-Ting Tu,
  • Ying-Ying Shao,
  • Yi Hua,
  • Yi Zhou and
  • Cheng-Xia Tan

20 June 2022

To develop new compounds with high activity, broad spectrum and low-toxicity, 17 benzamides substituted with quinoline-linked 1,2,4-oxadiazole were designed using the splicing principle of active substructures and were synthesized. The biological act...

  • Article
  • Open Access
4 Citations
4,246 Views
20 Pages

Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes

  • Anna Clua,
  • Santiago Grijalvo,
  • Namrata Erande,
  • Swati Gupta,
  • Kristina Yucius,
  • Raimundo Gargallo,
  • Stefania Mazzini,
  • Muthiah Manoharan and
  • Ramon Eritja

20 June 2022

The development of oligonucleotide conjugates for in vivo targeting is one of the most exciting areas for oligonucleotide therapeutics. A major breakthrough in this field was the development of multifunctional GalNAc-oligonucleotides with high affini...

of 32

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Molecules - ISSN 1420-3049