You are currently viewing a new version of our website. To view the old version click .

Molecules, Volume 26, Issue 8

April-2 2021 - 296 articles

Cover Story: Current therapies for bone metastases, targeting bone remodeling, are mainly palliative. Aside from these treatments, systemic radiation has also been used to target every bone metastatic lesion. Bone seeking beta minus particle-emitting radiopharmaceuticals have shown pain relief, but they have failed to extend overall survival of patients with bone metastases. However, recent clinical trials indicate that radium-223 dichloride, an alpha particle-emitting radiopharmaceutical, improves the overall survival of bone metastatic prostate cancer patients. This success has renewed interest in targeted alpha particle therapy development for bone metastasis, and current data suggest that targeted alpha particle therapies hold promise in improving clinical outcomes in cancer patients with bone metastases. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (296)

  • Article
  • Open Access
8 Citations
4,705 Views
14 Pages

19 April 2021

The geographical origin of honey affects its composition, which is of key importance for the health-promoting properties and safety of the product. European regulations clearly define the physicochemical requirements for honey that determine the micr...

  • Review
  • Open Access
14 Citations
6,343 Views
21 Pages

The Biological Effects of Forsythia Leaves Containing the Cyclic AMP Phosphodiesterase 4 Inhibitor Phillyrin

  • Sansei Nishibe,
  • Kumiko Mitsui-Saitoh,
  • Junichi Sakai and
  • Takahiko Fujikawa

19 April 2021

Forsythia fruit (Forsythia suspensa Vahl (Oleaceae)) is a common component of Kampo medicines for treating the common cold, influenza, and allergies. The main polyphenolic compounds in the leaves of F. suspensa are pinoresinol β-d-glucoside, phillyri...

  • Article
  • Open Access
10 Citations
2,821 Views
17 Pages

Polymer–Colloid Complexes Based on Cationic Imidazolium Amphiphile, Polyacrylic Acid and DNA Decamer

  • Darya A. Kuznetsova,
  • Dinar R. Gabdrakhmanov,
  • Denis M. Kuznetsov,
  • Svetlana S. Lukashenko,
  • Valery M. Zakharov,
  • Anastasiia S. Sapunova,
  • Syumbelya K. Amerhanova,
  • Anna P. Lyubina,
  • Alexandra D. Voloshina and
  • Diana V. Salakhieva
  • + 1 author

19 April 2021

The solution behavior and physicochemical characteristics of polymer–colloid complexes based on cationic imidazolium amphiphile with a dodecyl tail (IA-12) and polyacrylic acid (PAA) or DNA decamer (oligonucleotide) were evaluated using tensiometry,...

  • Article
  • Open Access
8 Citations
4,150 Views
7 Pages

Quantification of Intracellular Thiols by HPLC-Fluorescence Detection

  • Hiroki Yamamoto,
  • Takuya Fujiwara,
  • Takashi Funatsu and
  • Makoto Tsunoda

19 April 2021

Biothiols, such as cysteine and glutathione, play important roles in various intracellular reactions represented by the redox equilibrium against oxidative stress. In this study, a method for intracellular thiol quantification using HPLC-fluorescence...

  • Article
  • Open Access
3 Citations
4,226 Views
15 Pages

UV-Cured Antibacterial Hydrogels Based on PEG and Monodisperse Heterofunctional Bis-MPA Dendrimers

  • Patrik Stenström,
  • Yanmiao Fan,
  • Yuning Zhang,
  • Daniel Hutchinson,
  • Sandra García-Gallego and
  • Michael Malkoch

19 April 2021

Bacterial infections are one of the major threats to human health due to the raising crisis of antibiotic resistance. Herein, second generation antibacterial heterofunctional dendrimers based on 2,2-bis(methylol)propionic acid were synthesized. The d...

  • Article
  • Open Access
34 Citations
4,275 Views
18 Pages

19 April 2021

Given the health-beneficial properties of compounds from hop, there is still a growing trend towards developing successful extraction methods with the highest yield and also receiving the products with high added value. The aim of this study was to d...

  • Article
  • Open Access
3 Citations
2,796 Views
10 Pages

Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives

  • Guoxiong Hua,
  • Cameron L. Carpenter-Warren,
  • David B. Cordes,
  • Alexandra M. Z. Slawin and
  • J. Derek Woollins

19 April 2021

A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl)...

  • Review
  • Open Access
88 Citations
9,118 Views
19 Pages

19 April 2021

Millions of people around the world suffer from psychiatric illnesses, causing unbearable burden and immense distress to patients and their families. Accumulating evidence suggests that inflammation may contribute to the pathophysiology of psychiatri...

  • Article
  • Open Access
35 Citations
6,771 Views
18 Pages

Melissa officinalis L. Aqueous Extract Exerts Antioxidant and Antiangiogenic Effects and Improves Physiological Skin Parameters

  • Simona Sipos,
  • Elena-Alina Moacă,
  • Ioana Zinuca Pavel,
  • Ştefana Avram,
  • Octavian Marius Crețu,
  • Dorina Coricovac,
  • Roxana-Marcela Racoviceanu,
  • Roxana Ghiulai,
  • Ramona Daniela Pană and
  • Codruţa Marinela Şoica
  • + 3 authors

19 April 2021

Melissa officinalis (MO) is a medicinal plant well-known for its multiple pharmacological effects, including anti-inflammatory, anticancer and beneficial effects on skin recovery. In this context, the present study was aimed to investigate the in vit...

  • Article
  • Open Access
6 Citations
3,803 Views
12 Pages

Fully Automated Synthesis of Novel TSPO PET Imaging Ligand [18F]Fluoroethyltemazepam

  • Dario Fiorenza,
  • Emanuele Nicolai,
  • Carlo Cavaliere,
  • Ferdinando Fiorino,
  • Giovanna Esposito and
  • Marco Salvatore

19 April 2021

Introduction: Benzodiazepines, including temazepam are described as TSPO antagonists. In fact, TSPO was initially described as a peripheral benzodiazepine receptor (PBR) with a secondary binding site for diazepam. TSPO is a potential imaging target o...

of 30

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Molecules - ISSN 1420-3049