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Molecules, Volume 25, Issue 19

October-1 2020 - 239 articles

Cover Story: This work focuses on the synthesis of a novel Bi(III)-Cu(II) aminohydroximate complex (derived from tyrosinehydroxamic acid) which belongs to a family of 15-MC-5 metallacrowns. They feature a snowflake-like structure with the neutral ring bearing five {Cu(II)-N-O} fragments, where five hydroximate oxygen atoms encapsulate a large metal ion. The ligand scaffold prefers early Ln3+ and Bi3+, which are characterized by the same charge and similar ionic radii. DFT calculations predict moderate affinity (16–20 kcal/mol per bond) of Bi3+ or La3+ to the metallamacrocycle, with the order Bi3+ < La3+. Thus, the 15-MC-5 Bi(III) metallacrown appears to represent a stable water-soluble system which can provide potential biomedical applications. View this paper
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Articles (239)

  • Article
  • Open Access
18 Citations
3,774 Views
16 Pages

7 October 2020

Moscatilin can protect rat pheochromocytoma cells against methylglyoxal-induced damage. Elimination of the effect of advanced glycation end-products (AGEs) but activation of AMP-activated protein kinase (AMPK) are the potential therapeutic targets fo...

  • Article
  • Open Access
14 Citations
3,970 Views
15 Pages

Flavonoid Profiles of Two New Approved Romanian Ocimum Hybrids

  • Fanica Balanescu,
  • Maria Daniela Ionica Mihaila,
  • Geta Cârâc,
  • Bianca Furdui,
  • Costel Vînătoru,
  • Sorin Marius Avramescu,
  • Elena Lacramioara Lisa,
  • Mihaela Cudalbeanu and
  • Rodica Mihaela Dinica

7 October 2020

Basil (Ocimum spp.) is a traditional herbal medicine abundant in antioxidants such as phenolic compounds. As part of a diet, this herb is proved to have some roles in decreasing the risk of cancer, and in the treatment of inflammation and neurodegene...

  • Feature Paper
  • Review
  • Open Access
58 Citations
8,602 Views
42 Pages

ATP-Binding and Hydrolysis in Inflammasome Activation

  • Christina F. Sandall,
  • Bjoern K. Ziehr and
  • Justin A. MacDonald

7 October 2020

The prototypical model for NOD-like receptor (NLR) inflammasome assembly includes nucleotide-dependent activation of the NLR downstream of pathogen- or danger-associated molecular pattern (PAMP or DAMP) recognition, followed by nucleation of hetero-o...

  • Article
  • Open Access
22 Citations
5,633 Views
12 Pages

Electrografting of 4-Carboxybenzenediazonium on Glassy Carbon Electrode: The Effect of Concentration on the Formation of Mono and Multilayers

  • Sereilakhena Phal,
  • Kenichi Shimizu,
  • Daniel Mwanza,
  • Philani Mashazi,
  • Andrey Shchukarev and
  • Solomon Tesfalidet

7 October 2020

Grafting of electrodes with diazonium salts using cyclic voltammetry (CV) is a well-established procedure for surface modification. However, little is known about the effect of the concentration of the diazonium salt on the number of layers grafted o...

  • Article
  • Open Access
23 Citations
5,557 Views
15 Pages

Essential Oil Compositions of Three Invasive Conyza Species Collected in Vietnam and Their Larvicidal Activities against Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus

  • Tran Minh Hoi,
  • Le Thi Huong,
  • Hoang Van Chinh,
  • Dang Viet Hau,
  • Prabodh Satyal,
  • Thieu Anh Tai,
  • Do Ngoc Dai,
  • Nguyen Huy Hung,
  • Vu Thi Hien and
  • William N Setzer

7 October 2020

Mosquito-borne infectious diseases are a persistent problem in tropical regions of the world, including Southeast Asia. Vector control has relied principally on synthetic insecticides, but these have detrimental environmental effects and there is an...

  • Article
  • Open Access
27 Citations
5,426 Views
14 Pages

Topical Application of Aronia melanocarpa Extract Rich in Chlorogenic Acid and Rutin Reduces UVB-Induced Skin Damage via Attenuating Collagen Disruption in Mice

  • Young Her,
  • Tae-Kyeong Lee,
  • Jong Dai Kim,
  • Bora Kim,
  • Hyejin Sim,
  • Jae-Chul Lee,
  • Ji Hyeon Ahn,
  • Joon Ha Park,
  • Ji-Won Lee and
  • Junkee Hong
  • + 2 authors

7 October 2020

Aronia melanocarpa, a black chokeberry, contains high levels of phenolic acids and polyphenolic flavonoids and displays antioxidative and anti-inflammatory effects. Through high-performance liquid chromatography for extracts from Aronia melanocarpa,...

  • Article
  • Open Access
24 Citations
5,375 Views
10 Pages

7 October 2020

The Maillard reaction intermediates and related phytochemicals in garlic (Allium sativum L.), which was heated for various lengths of time, using X-band (9 GHz) electron paramagnetic resonance (EPR) and high performance liquid chromatography (HPLC) w...

  • Article
  • Open Access
8 Citations
4,310 Views
18 Pages

7 October 2020

Background: Preterm birth is a known leading cause of neonatal mortality and morbidity. The underlying causes of pregnancy-associated complications are numerous, but infection and inflammation are the essential high-risk factors. However, there are n...

  • Article
  • Open Access
3 Citations
3,313 Views
15 Pages

Hemocyanin Modification of Chitosan Scaffolds with Calcium Phosphate Phases Increase the Osteoblast/Osteoclast Activity Ratio—A Co-Culture Study

  • Benjamin Kruppke,
  • Christiane Heinemann,
  • Jana Farack,
  • Simy Weil,
  • Eliahu David Aflalo,
  • Amir Sagi and
  • Thomas Hanke

7 October 2020

The ongoing research on biomaterials that support bone regeneration led to the quest for materials or material modifications that can actively influence the activity or balance of bone tissue cells. The bone biocompatibility of porous chitosan scaffo...

  • Article
  • Open Access
8 Citations
3,059 Views
17 Pages

7 October 2020

Amomi Fructus is widely used to treat digestive disorders, and Amomum villosum, A. villosum var. xanthioides, and A. longiligulare are permitted medicinally in national pharmacopeias. However, there are a variety of adulterants present in herbal mark...

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Molecules - ISSN 1420-3049