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Fluorimetric Properties of 3-Aminoflavone Biomolecule (3-AF). X-ray Crystal Structure of New Polymorph of 3-AF

1
Department of Analytical Chemistry, 1 Muszyńskiego Str., Medical University of Lodz, 90-151 Lodz, Poland
2
Department of Bioinorganic Chemistry, 1 Muszyńskiego Str., Medical University of Lodz, 90-151 Lodz, Poland
3
Institute of General and Ecological Chemistry, Łódź University of Technology, 116 Żeromskiego St., 90-924 Lodz, Poland
4
Department of Toxicology, 1 Muszyńskiego Str., Medical University of Lodz, 90-151 Lodz, Poland
*
Authors to whom correspondence should be addressed.
Academic Editor: Josef Jampilek
Molecules 2019, 24(16), 2927; https://doi.org/10.3390/molecules24162927
Received: 2 July 2019 / Revised: 6 August 2019 / Accepted: 12 August 2019 / Published: 13 August 2019
(This article belongs to the Special Issue Heterocycles in Medicinal Chemistry)
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Abstract

The crystal structure of the new polymorphic form of 3-aminoflavone (3-AF) has been determined by single crystal X-ray diffraction. This report presents results of fluorimetric studies on 3-AF in methanol and aquatic solvents. Based on 3D fluorescence emission spectra, optimal values for excitation (λex) and emission/analytical (λem) wavelength, the analytical concentration range as well as the range of concentration quenching for the studied compound were established. Moreover, the limit of detection (LOD) and the limit of quantification (LOQ) were determined. The results were compared with those obtained using the standard UV-Vis absorption spectrophotometric method. The effect of acidity (pH) and the concentration of halide anions (chlorides, bromides, iodides and fluorides) on fluorescence quenching were analysed. View Full-Text
Keywords: 3-aminoflavone; X-ray crystallography; fluorescence; LOD (limit of detection); LOQ (limit of quantification); concentration quenching 3-aminoflavone; X-ray crystallography; fluorescence; LOD (limit of detection); LOQ (limit of quantification); concentration quenching
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Pająk, W.; Fabijańska, M.; Wojciechowski, J.; Wolf, W.M.; Kilanowicz, A.; Brzezińska, E.; Ochocki, J. Fluorimetric Properties of 3-Aminoflavone Biomolecule (3-AF). X-ray Crystal Structure of New Polymorph of 3-AF. Molecules 2019, 24, 2927.

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