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Review

A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides

1
School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
2
School of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
*
Author to whom correspondence should be addressed.
Molecules 2018, 23(5), 1170; https://doi.org/10.3390/molecules23051170
Received: 14 April 2018 / Revised: 7 May 2018 / Accepted: 8 May 2018 / Published: 14 May 2018
(This article belongs to the Section Natural Products Chemistry)
Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibiricum (PS), a natural plant used in traditional Chinese medicine, has various functions associated with a number of its components. There are many compositions in PS including polysaccharides, steroids, anthraquinone, alkaloids, cardiac glycosides, lignin, vitamins, various acids, and so on. Of these, polysaccharides play a significant role in PS-based therapeutics. This article summarizes Polygonatum sibiricum polysaccharides (PSP) have many pharmacological applications and biological activities, such as their antioxidant activity, anti-aging activity, an anti-fatigue effect, immunity enhancement effect, antibacterial effect, anti-inflammatory effect, hypolipidemic and antiatherosclerotic effects, anti-osteoporosis effect, liver protection, treatment of diabetes mellitus (DM), anti-cancer effect, and may help prevent Alzheimer’s disease, and so on. This review summarized the extraction method, purification method, compositions, pharmacological applications, biological activities, biosynthesis, and prospects of PSP, providing a basis for further study of PS and PSP. View Full-Text
Keywords: Polygonatum sibiricum polysaccharides (PSP); compositions; pharmacological applications; biological activity; biosythesis; prospects Polygonatum sibiricum polysaccharides (PSP); compositions; pharmacological applications; biological activity; biosythesis; prospects
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MDPI and ACS Style

Cui, X.; Wang, S.; Cao, H.; Guo, H.; Li, Y.; Xu, F.; Zheng, M.; Xi, X.; Han, C. A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides. Molecules 2018, 23, 1170. https://doi.org/10.3390/molecules23051170

AMA Style

Cui X, Wang S, Cao H, Guo H, Li Y, Xu F, Zheng M, Xi X, Han C. A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides. Molecules. 2018; 23(5):1170. https://doi.org/10.3390/molecules23051170

Chicago/Turabian Style

Cui, Xiaowei, Shiyuan Wang, Hui Cao, Hong Guo, Yujuan Li, Fangxue Xu, Mengmeng Zheng, Xiaozhi Xi, and Chunchao Han. 2018. "A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides" Molecules 23, no. 5: 1170. https://doi.org/10.3390/molecules23051170

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