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Molecules 2017, 22(9), 1475;

Cyclodextrin-Catalyzed Organic Synthesis: Reactions, Mechanisms, and Applications

School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China
Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Yinchuan 750004, China
These authors contributed equally to this work.
Authors to whom correspondence should be addressed.
Received: 2 August 2017 / Accepted: 2 September 2017 / Published: 7 September 2017
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Cyclodextrins are well-known macrocyclic oligosaccharides that consist of α-(1,4) linked glucose units and have been widely used as artificial enzymes, chiral separators, chemical sensors, and drug excipients, owing to their hydrophobic and chiral interiors. Due to their remarkable inclusion capabilities with small organic molecules, more recent interests focus on organic reactions catalyzed by cyclodextrins. This contribution outlines the current progress in cyclodextrin-catalyzed organic reactions. Particular emphases are given to the organic reaction mechanisms and their applications. In the end, the future directions of research in this field are proposed. View Full-Text
Keywords: cyclodextrin; catalysis; mechanism; green chemistry; organic reaction; asymmetric reaction cyclodextrin; catalysis; mechanism; green chemistry; organic reaction; asymmetric reaction

Scheme 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Bai, C.C.; Tian, B.R.; Zhao, T.; Huang, Q.; Wang, Z.Z. Cyclodextrin-Catalyzed Organic Synthesis: Reactions, Mechanisms, and Applications. Molecules 2017, 22, 1475.

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